Introduction: Limb amputation is a major life changing surgery used in many disciplines as a planned primary procedure or as a salvage procedure in tumours, trauma, and peripheral vascular disease. However, amputation carries a high rate of wound complications such as infection, dehiscence, and impaired healing. These complications may result in further surgical intervention, prolonged hospitalisation, and decreased quality of life for patients. Whilst the use of negative pressure wound therapy (NPWT) in the treatment of chronic wounds has demonstrated improved wound outcomes by increased wound healing, wound shrinkage, and decreasing wound oedema; literature for the use of NPWT in amputations is scarce.Aim: To evaluate the wound healing outcomes of patients after lower limb amputation treated with and without the use of NPWT. Patients for the intervention group were chosen from an amputation database whom had received NPWT from 2015 to 2017. A control group was established by an independent investigator from a prospective amputation database whilst matching patients in the intervention group for age, gender, type of amputation and method of closure. Outcomes assessed were the presence of wound complications, additional surgical procedures, and drainage volumes.Results: Patients in both the intervention group (n=9) and control group (n=9) were well matched for demographics. The intervention group had a higher yield of mean drainage volumes compared to the control group of 285.6ml and 220.0ml respectively. Additionally, the intervention group demonstrated fewer patients with wound complications compared to the control group at 2 versus 5 patients respectively.
Conclusion:The data presented above demonstrates a positive trend in the reduction of wound complications with the use of NPWT. Despite being statistically insignificant, we believe that there is evidence to suggest the potential of NPWT in amputation therapy. Therefore, a prospective investigation with a larger sample size is warranted for further assessment of the effectiveness of NPWT as routine therapy for amputations.