Wound Infections

Torpy, Janet M.

doi:10.1001/jama.294.16.2122

Cited by 27 publications

(25 citation statements)

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“…Male patients between the age categories of 21-30 years recorded the most significant infection rate (21.43%) on sex versus age group basis ( Table 1). Similar findings by [24] was reported and they assert that age significantly affects the prevalence of wound infections, since adolescents and active-age adults are usually the ones involved in much physical activities such as sports and farming which may expose them more to injuries and infections. Infants and older age individuals are also considered at risk of acquiring wound infections because of the decrease in immune competence with age [25,26], and infants have their immune system at the developmental stage.…”

Section: Prevalence Of Proteus Spp In Relation To Patients' Demographsupporting

confidence: 85%

Plasmid Profile Analysis of Multi-drug Resistant Proteus spp isolated from Patients with Wound Infection in Northeastern Nigeria

Tom

Agbo

Faruk

et al. 2018

IJPR

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Aims:We analysed the prevalence of plasmid mediated multidrug resistance among Proteus spp isolated from wound infection patients attending healthcare centers in Maiduguri. Methodology: 320 wound swab samples were collected from August 2016 to June 2017, and investigated via microscopy, cultured on Blood agar and MacConkey agar. Suspected Proteus spp isolates were further confirmed using biochemical tests. Kirby bauer disc diffusion test was used to determine the antimicrobial susceptibility pattern. Isolates confirmed to be multidrug resistant (MDR) were subjected to gel electrophoresis for the determination of plasmid profile. Results: Twenty eight (28) samples yielded Proteus spp, giving a prevalence rate of 8.75%. Original Research Article2 =7.342, p>0.01). Plasmid profile analysis revealed that 72.22% of the MDR isolates harbour plasmids with a DNA fragment size of 100 bp and a molecular weight of 31ng/10µl. An average of 7.22% of MDR isolates were cured of their plasmids while an average of 56.67% of MDR isolates resisted curing. Conclusion: Here, we report a high prevalence of multidrug resistance and a high rate of plasmid carrying strains of Proteus spp in wounds of hospitalised patients. We suggest that there is a role played by plasmid in the mediation of multidrug resistance among the MDR Proteus spp isolated, where the majority of the MDR isolates observed carry plasmids.

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Section: Prevalence Of Proteus Spp In Relation To Patients' Demographsupporting

confidence: 85%

Plasmid Profile Analysis of Multi-drug Resistant Proteus spp isolated from Patients with Wound Infection in Northeastern Nigeria

Tom

Agbo

Faruk

et al. 2018

IJPR

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“…Surgical site infection causes global Health Challenges [1]. Most bacteria enter the wound through external contamination from the environment, example; the bed, patient's body fluid, dressings, hands and or healthcare provider [3]. It [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…Most bacteria enter the wound through external contamination from the environment, example; the bed, patient's body fluid, dressings, hands and or healthcare provider [3]. It [3,4]. Due to the increasing emergence of multi antibiotics resistance, wound isolates are causing huge public health concerns hence, the need for exploring some necessary alternatives for treatment of wound infections.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and Antimicrobial Activities of Bryophyllum pinnatum and Vernonia amygdalina Leaves Extracts on Selected Microbial Isolates from Wound Infection

Okele

Wokem

Godwin

2019

JAMB

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Introduction: The therapeutic actions of plants may be due to the presence of some phytochemical components. Due to the increasing emergence of multi antibiotics resistance, wound pathogens are causing huge public health concerns. There is need for exploring some necessary alternatives for treatment of wound infections. Aim: This study investigated the phytochemical and antimicrobial activities of Vernonia amygdalina and Bryophyllum pinnatum leaves extracts on Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus isolates from wound infection. Methodology: The fresh leaves of both plants were extracted using Sofowora method and the phytochemicals were screened. Different concentrations of the extract, antibiotic and ethanol were tested against the isolates using disc diffusion technique. Results: Alkaloids, flavonoids, tannins, anthraquinone and fixed oils were present in the both plant extracts but saponins were only found in V. amygdalina and cardenolide were only in B. pinnatum. Quantitatively, all the phytochemicals investigated in the study were present with V. amygdalina having the highest level of saponins than Bryophyllum pinnatum (P<0.05) and low steroids with P=0.2879 (P>0.05).The crude extract of V. amygdalina had the highest zone of inhibition compared to aqueous and ethanol extracts at 75 mg/ml concentration (P<0.05) but generally, the ethanol extracts of both plants had more inhibitions at varying concentrations. Thus comparing the antimicrobial activity of various extracts of both plants on the wound isolates and the controls (antibiotics and ethanol), there was significant variation in their zones of inhibition produce (P<0.05). Conclusion: The results show that the zone of inhibition increases with the concentrations of the extracts. Therefore, the antimicrobial effect of these plants may depend on the concentration of the extract and the solvent used for extraction. This study showed that B. pinnatum and V. amygdalina could be used as an alternative therapy to antibiotics to treat wound infection caused by P. aeruginosa, E. coli and S. aureus.

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“…Human skin provides protection for the body from external environment, preventing dehydration, regulates body temperature, detects cutaneous sensation, and synthesizes vitamin D (Tortora and Derrickson, 2008). The skin barrier can be broken, such as from a wound (Torpy et al, 2005). There are many types wound which have been classified into two groups, open and closed wound (Chandler, 2011).…”

Section: Introduction:-mentioning

confidence: 99%

Comperative Study of Neem, Garlic, and Henna With Antibiotic Nebanol® Against Artificial Wound in Guinea Pigs.

Nyeem¹,

Taher²,

Islam³

et al. 2016

IJAR

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Wound Infections

Cited by 27 publications

References 0 publications

Plasmid Profile Analysis of Multi-drug Resistant Proteus spp isolated from Patients with Wound Infection in Northeastern Nigeria

Plasmid Profile Analysis of Multi-drug Resistant Proteus spp isolated from Patients with Wound Infection in Northeastern Nigeria

Phytochemical and Antimicrobial Activities of Bryophyllum pinnatum and Vernonia amygdalina Leaves Extracts on Selected Microbial Isolates from Wound Infection

Comperative Study of Neem, Garlic, and Henna With Antibiotic Nebanol® Against Artificial Wound in Guinea Pigs.

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