Wound infections and nasal colonization of staff with Staphylococcus aureus in Benin, Nigeria

Wemambu, S.N.C.

doi:10.1016/0195-6701(81)90047-5

Cited by 5 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was in agreement to some extent with those earlier reported by Wemambu (1981) and Yah et al (2004) who found S. aureus predominating followed by Proteus sp. However, in this study S. aureus constitutes 53.4% of the total isolates.…”

Section: Discussionsupporting

confidence: 83%

“…(3.7%) each. The spectrum of the organisms recovered in this study is similar to those earlier reported by Wemambu (1981).…”

Section: Discussionsupporting

confidence: 81%

“…P. aeruginosa showed a percentage susceptibility of 83.3-100% for ciprofloxacin, and < 50% for cloxacillin, erythromycin, tetracycline, cotrimoxazole, gentamicin and chloramphenicol. Finland (1984) isolated from staff nurses S. aureus and found that methicillin resistant S. aureus (MRSA) was relatively high in surgical wound patients, followed by Pseudomonas aeruginosa while Wemambu (1981) found that S. aureus isolated from noses of surgeons, theatre nurses and wounds were resistant to penicillin, streptomycin and tetracycline.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Patterns of antibiotics susceptibility of isolates and plasmid analysis of Staphylococcus from surgical site infections in Nigeria

Yah¹,

Yusuf²,

Tamano³

2009

International Journal of Biological and Chemical Sciences

View full text Add to dashboard Cite

There has been a significant increase in resistance of common bacterial isolates from surgical site infections in our community resulting in prolonged hospital stay, disability and deaths of patients. In this vein, we surveyed the antibiotic susceptibility profiles of aerobic bacterial isolates from postoperative wound infections and determined whether resistance in Staphylococcus aureus was genetically mediated. A total of 161 isolates were obtained from 153 swab samples of infected wounds using cultural, morphological, and biochemical characteristics. The predominant bacterial isolates were: S. aureus (53.4%), Escherichia coli (23.0%), Staphylococcus epidermidis (11.2%), Pseudomonas aeruginosa (5.0%), and species of Klebsiella and Proteus 3.7% each. On the whole: Escherichia coli, Klebsiella and Proteus showed similar antibiotic susceptibility patterns viz: 66.7-100% for ciprofloxacin, 66.7-100% gentamicin and 50-80% augmentin; and less than 50% for amoxacillin, erythromycin, tetracycline, cotrimoxazole, cloxacillin and chloramphenicol. S. aureus showed percentage susceptibility of 50-100% and Staphylococcus epidermidis (50-100%) for cloxacillin and augmentin, and less than 60% for amoxacillin, erythromycin, tetracycline, cotrimoxazole, gentamicin and chloramphenicol. Multi drug resistance (MDR) of S. aureus strains to at least three classes of the antibiotics used was about 70.5%. Four out of the 11 MDR S. aureus strains were found to harbor plasmids with varying molecular weights that ranged from 3.114 to 6.509 kb. One of the multi-drug resistant isolates still exhibited resistance even after curing. This showed that other genetic elements may also be involved in the acquisition of these forms of resistance other than plasmid elements.

show abstract

Section: Discussionsupporting

confidence: 83%

“…(3.7%) each. The spectrum of the organisms recovered in this study is similar to those earlier reported by Wemambu (1981).…”

Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Patterns of antibiotics susceptibility of isolates and plasmid analysis of Staphylococcus from surgical site infections in Nigeria

Yah¹,

Yusuf²,

Tamano³

2009

International Journal of Biological and Chemical Sciences

View full text Add to dashboard Cite

show abstract

“…While a study explained the role of S.aureus in wound infections and nasal carriage in staff of teaching hospital [11], another showed the resistance pattern of a set of nasal strains to commonly used antimicrobial agents [12], surprisingly; no studies that exploit molecular and statistical methods to explain the role of nasal carriage in transmission of S.aureus have been documented. In this present investigation, S.aureus colonization rates among medical students were assessed to indicate nasal carriage as a risk factor for successful transmission and development of staphylococcal infection in the country.…”

mentioning

confidence: 99%

Associated risk factors and pulsed field gel electrophoresis of nasal isolates of Staphylococcus aureus from medical students in a tertiary hospital in Lagos, Nigeria

Adesida¹,

Abioye²,

Bamiro³

et al. 2007

Braz J Infect Dis

View full text Add to dashboard Cite

Staphylococcus aureus infections are growing problems worldwide with important implications in hospitals. The organism is normally present in the nasal vestibule of about 35% of apparently healthy individuals and its carriage varies between different ethnic and age groups. Staphylococcal nasal carriage among health workers is particularly important to establish new clones and track origin of infections during outbreak situations. To determine the carriage rate and compare the pulsed field gel patterns of the strains, nasal swabs were collected from 185 medical students in a teaching hospital in Lagos, Nigeria. Isolates of S. aureus were tested for heamolysin production, methicillin sensitivity and Pulsed Field Gel Electrophoresis (PFGE) was performed. The results showed S.aureus nasal carrier rate of 14% with significant rate among males compared to females. All the isolates produced heamolysin. Antibiotic susceptibility pattern revealed that majority of the isolates was susceptible. Five strains (19%) harboured resistant determinants to penicillin and tetracycline. None of the strains was resistant to methicillin. 44% of the isolates typed by PFGE had type B, the most predominant pulsotype. PFGE A clone exhibited a single resistance phenotype suggesting a strong clonal relationship that could punctual an outbreak in the hospital. The results speculate that nasal carriage among medical personnel could be a function of various risk factors. Personal hygiene and behaviour may however be the means to reducing colonization and spread of S.aureus in our hospitals.

show abstract

Epidémiologie des infections des plaies opératoires à Staphylococcus aureus au CNHU de Cotonou : aspects bactériologiques

Makoutodé¹,

Ahoyo²,

Ahossi³

et al. 1994

Médecine et Maladies Infectieuses

View full text Add to dashboard Cite

Wound infections and nasal colonization of staff with Staphylococcus aureus in Benin, Nigeria

Cited by 5 publications

References 2 publications

Patterns of antibiotics susceptibility of isolates and plasmid analysis of Staphylococcus from surgical site infections in Nigeria

Patterns of antibiotics susceptibility of isolates and plasmid analysis of Staphylococcus from surgical site infections in Nigeria

Associated risk factors and pulsed field gel electrophoresis of nasal isolates of Staphylococcus aureus from medical students in a tertiary hospital in Lagos, Nigeria

Epidémiologie des infections des plaies opératoires à Staphylococcus aureus au CNHU de Cotonou : aspects bactériologiques

Contact Info

Product

Resources

About