2016
DOI: 10.1016/j.wndm.2016.02.004
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Wounds, burns, trauma, and injury

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Cited by 14 publications
(14 citation statements)
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“…1 The wound healing process can be categorized into three phases: tissue in°ammation, which starts upon injury and normally lasts between 3 and 4 days, followed by the proliferative stage that involves the development of new blood vessels, which may take up to weeks, and lastly the tissue remodeling phase that produces the scarring of tissue. 2 Previous literatures 3,4 have revealed that the microcirculation system of the wound and its surrounding tissues shows an acute hypoxic condition from the constriction and rechanneling of blood vessels away from this site during the onset of tissue injury to mitigate bleeding; the recovery of wound tissue oxygenation through angiogenesis following this step is essential for physiological healing. In chronic wounds, such as diabetic wounds, tissue oxygenation fails to be restored, thereby impairing the healing processes.…”
Section: Introductionmentioning
confidence: 99%
“…1 The wound healing process can be categorized into three phases: tissue in°ammation, which starts upon injury and normally lasts between 3 and 4 days, followed by the proliferative stage that involves the development of new blood vessels, which may take up to weeks, and lastly the tissue remodeling phase that produces the scarring of tissue. 2 Previous literatures 3,4 have revealed that the microcirculation system of the wound and its surrounding tissues shows an acute hypoxic condition from the constriction and rechanneling of blood vessels away from this site during the onset of tissue injury to mitigate bleeding; the recovery of wound tissue oxygenation through angiogenesis following this step is essential for physiological healing. In chronic wounds, such as diabetic wounds, tissue oxygenation fails to be restored, thereby impairing the healing processes.…”
Section: Introductionmentioning
confidence: 99%
“…Consequently, scars in most Asian patients require longer maturing [2,3]. Generally, wounds that do not heal within 2-3 weeks are considered most at risk for excessive scar formation [1,[4][5][6]. Asians are more likely to develop hypertrophic scars compared with Caucasians, and Africans are more likely to develop hypertrophic scars than Asians [5,7].…”
Section: Introductionmentioning
confidence: 99%
“…Scars can be disfiguring and aesthetically unpleasant. The side effects of scarring may include severe itching, tenderness, pain, sleep disturbances, anxiety, depression, and disruption of daily activities [5]. Scarring is a natural part of the healing process after an injury.…”
Section: Introductionmentioning
confidence: 99%
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