Wrist Circumference: An Independent Predictor of Both Insulin Resistance and Chronic Kidney Disease in an Elderly Population

Abstract

Background and aim: It was recently reported that wrist circumference is associated with insulin resistance (IR) both in children and adults. We aimed to evaluate whether wrist circumference is a useful anthropometrical parameter for the evaluation of IR in an elderly population. Material and method: We performed a study on 40 subjects, 20 with type 2 diabetes (T2D) and 20 control subjects. IR was evaluated using the homeostasis model assessment of insulin resistance (HOMA-IR). We measured the following anthropometrical parameters: weight, height, waist circumference (WC), hip circumference, wrist circumference, waist to hip ratio (WHR), waist to height ratio (WHtR), body mass index (BMI) and body adiposity index (BAI). Results: We found statistically significant differences between the subjects with T2D and the control group for all the analyzed parameters. Statistically significant correlations between all the anthropometrical parameters and HOMA-IR were observed. However, only WC was an independent predictor of IR. Wrist circumference was the only parameter negatively correlated with the estimated glomerular filtration rate (eGFR). Furthermore, this measurement was an independent predictor of chronic kidney disease (CKD) in the studied subjects. Conclusion: Wrist circumference can be used in the general practice as a surrogate marker of IR in the elderly, being both easily determined and a cost-free method

Correlation of wrist circumference with waist circumference and body mass index in adults with early-onset type 2 diabetes mellitus

“…Differently from waist circumference, wrist circumference measurement is not affected by clothing, respiration or by postprandial state which can interfere with the determination of waist circumference. 24,25 Measurement of wrist circumference may supplement in assessing generalised and abdominal obesity (and indirectly insulin resistance), when valid weighing machine is not easily available in the field for measuring BMI or accurate measurement of waist circumference is not possible in communities because of lack of privacy for removing cloths especially in women.…”

Excellent Intra and Inter-Observer Reproducibility of Wrist Circumference Measurements in Obese Children and Adolescents

“…The easy and simple way of measuring wrist circumference is a considerable advantage in everyday clinical practice compared to the classical anthropometrical measurement such as BMI or waist circumference. Another advantage of using wrist circumference compared to the common anthropometric measures is that reflecting a skeletal frame size, it changes slightly through time [ 24 ].…”

“…Differently from waist circumference, wrist circumference measurement is not affected by clothing, respiration or by postprandial state which can interfere with the determination of waist circumference [ 24 ]. To date, there is no agreement on the optimal anatomical sites to measure waist circumference in children [ 25 ].…”

Perkembangan Diabetes Melitus Tipe 2 dari Prediabetes di Bogor, Jawa Barat

“…Hal ini ditunjukkan dengan hasil penelitian Mitrea dkk bahwa lingkar perut berkorelasi dengan IR yang dihitung dengan HOMA-IR (p=0.014). 26 Sementara itu, DM dan hipertensi merupakan coexisting. Faktor yang berkontribusi terhadap peningkatan koeksistensi DM dan hipertensi antara lain adalah obesitas.…”