Wuchereria bancrofti and cytology: A retrospective analysis of 110 cases from an endemic area

Prasoon, Dev; Agrawal, Parimal

doi:10.4103/joc.joc_59_20

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…An alternative migration route used by microfilariae to arrive at the processus vaginalis may be via the lymphatic vessels; observed, for example, in Brugia malayi infections ( 42 ). Interestingly, microfilariae of Wuchereria bancrofti have also been shown to infect testicular tissue ( 43 , 44 ) and follicular fluid in humans ( 45 ).…”

Section: Discussionmentioning

confidence: 99%

Case report: Filarial infection of a parti-coloured bat: Litomosa sp. adult worms in abdominal cavity and microfilariae in bat semen

Pikula,

Piacek,

Bandouchova

et al. 2023

Front. Vet. Sci.

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BackgroundFilarial infections have been understudied in bats. Likewise, little is known about pathogens associated with the reproductive system in chiropterans. While semen quality is critical for reproductive success, semen-borne pathogens may contribute to reproductive failure.MethodsFor the first time we performed electroejaculation and used computer-assisted semen analysis to provide baseline data on semen quality in a parti-coloured bat (Vespertilio murinus).ResultsThe semen quality values measured in the V. murinus male appeared high (semen concentration = 305.4 × 106/mL; progressive and motile sperm = 46.58 and 60.27%, respectively). As an incidental finding, however, microfilariae were observed in the bat semen examined. At necropsy, eight adult filarial worms, later genetically identified as Litomosa sp., were found in the peritoneal cavity, close to the stomach, of the same particoloured bat male dying as a result of dysmicrobia and haemorrhagic gastroenteritis in a wildlife rescue centre. Histopathology revealed microfilariae in the testicular connective tissue and the epidydimal connective and fat tissues. A PCR assay targeting cytochrome c oxidase subunit 1 confirmed that adult worms from the peritoneal cavity and testicular microfilariae were of the same filarial species. Mildly engorged argasid mite larvae attached to the bat skin proved negative for filarial DNA and the adult filarial worms proved negative for endosymbiont Wolbachia.ConclusionWhile the standard filarial life cycle pattern involves a vertebrate definitive host and an invertebrate vector, represented by a blood-sucking ectoparasite, our finding suggests that microfilariae of this nematode species may also be semen-borne, with transmission intensity promoted by the polygynous mating system of vespertilionid bats in which an infected male mates with many females during the autumn swarming. Presence of microfilariae may be expected to decrease semen quality and transmission via this route may challenge the success of reproductive events in females after mating. Further investigation will be necessary to better understand the bat-parasite interaction and the life cycle of this filarial worm.

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Section: Discussionmentioning

confidence: 99%

Case report: Filarial infection of a parti-coloured bat: Litomosa sp. adult worms in abdominal cavity and microfilariae in bat semen

Pikula,

Piacek,

Bandouchova

et al. 2023

Front. Vet. Sci.

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“…Micro laria have also been found in the tumour uid of patients with various cancer types according to Prasoon et al (2020). Lymphatic lariasis is a major public health issue in tropical countries such as India, China, the West Indies, Japan, and parts of Africa.…”

Section: Introductionmentioning

confidence: 99%

Breast filariasis presenting fibroadenoma like nodules: a rare diagnosis

2022

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India has still not eradicated lariasis, which is still endemic throughout the country. This study focuses on the breast as a non-typical but not uncommon site of breast disease characterized by nematodes causing obstruction of lymphatic vessels caused by lariasis. The case described herein involves a 26year-old married female who presented as a subcutaneous nodule in her left breast. Clinical interrogation of this case as part of the pathological diagnosis, phlebotomy was performed by venepuncture in order to examine peripheral blood smears under a microscope. Nonetheless, the peripheral blood smear did not show micro lariae of the disease. Furthermore, ne needle aspiration cytology was also performed to identify possible things for the study. It was diagnosed that lariasis with broadenoma was found to be carrying micro lariae present in ne-needle aspiration cytology smears of various lesions. Conclusively the lymphatic swelling was con rmed to be caused by Wuchereria bancrofti in ne-needle aspiration cytology examination without evidence in peripheral blood smears. It was shown that the subject had lariasis, and the patient responded well to daily treatment with diethylcarbamazine citrate for 42 days.

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Breast Filariasis Presenting Fibroadenoma like Nodules: A Rare Diagnosis

Kumar

Priyadharisini

Singh

2022

Preprint

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India has still not eradicated filariasis, which is still endemic throughout the country. This study focuses on the breast as a non-typical but not uncommon site of breast disease characterized by nematodes causing obstruction of lymphatic vessels caused by filariasis. The case described herein involves a 26-year-old married female who presented as a subcutaneous nodule in her left breast. Clinical interrogation of this case as part of the pathological diagnosis, phlebotomy was performed by venepuncture in order to examine peripheral blood smears under a microscope. Nonetheless, the peripheral blood smear did not show microfilariae of the disease. Furthermore, fine needle aspiration cytology was also performed to identify possible things for the study. It was diagnosed that filariasis with fibroadenoma was found to be carrying microfilariae present in fine-needle aspiration cytology smears of various lesions. Conclusively the lymphatic swelling was confirmed to be caused by Wuchereria bancrofti in fine-needle aspiration cytology examination without evidence in peripheral blood smears. It was shown that the subject had filariasis, and the patient responded well to daily treatment with diethylcarbamazine citrate for 42 days.

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Wuchereria bancrofti and cytology: A retrospective analysis of 110 cases from an endemic area

Cited by 3 publications

References 11 publications

Case report: Filarial infection of a parti-coloured bat: Litomosa sp. adult worms in abdominal cavity and microfilariae in bat semen

Case report: Filarial infection of a parti-coloured bat: Litomosa sp. adult worms in abdominal cavity and microfilariae in bat semen

Breast filariasis presenting fibroadenoma like nodules: a rare diagnosis

Breast Filariasis Presenting Fibroadenoma like Nodules: A Rare Diagnosis

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