Medical imaging applications using X-and gamma-rays have reached outstanding levels of complexity and performance, thanks to technology achievements in the fields of radiography, tomography and high resolution synchrotron devices. The operability of the related instrumentation resides in the availability of highly qualified specialists, as well as of medical doctors for diagnoses and treatment. This is a problem for personnel working in difficult ambient conditions as can be found in remote sites like Arctica, Antarctica and under-populated, desolated or mountainous regions on Earth. Astronauts, during long permanence at the Space Station or on future mission to Mars are potentially subject to risks such as traumas, fractures or diseases which would require semi-automated, easyto-handle application of X-ray radiographic devices. For this purpose, the possible use of imaging instrumentation based on solid state detectors is discussed with special regard to CdZnTe pixel devices, now available with sub-mm resolution. The use of these semiconductor detectors will also allow to perform image diagnostics at much lower doses compared to the current plate-based radiographic techniques.