This study investigated the microstructure and mechanical properties of frictional welded joints between SAF 2205 duplex stainless steel and AISI 1045 medium carbon steel. The welded joints were fabricated by varying the friction pressure, friction time, and keeping the forging pressure, forging time and rotational speed as constant to obtain a constant range of welding temperature (780-800 °C). The results revealed that as the friction pressure increases and friction time decreases, weld interface hardness value, tensile strength and ductility increases. Also the hardness profiles present that weld interfaces exhibit higher hardness values than that of the two base metals. It was found that the highest efficiency of weld joint achieved was 93%, while the lowest was 76%. In addition, all welded specimens failed in the weld region. The microstructure analyses were carried out using optical microscopy and scanning electron microscopy equipped with energy dispersive spectroscopy.