The Birkhoff-Maltsev problem asks for a characterization of those lattices each of which is isomorphic to the lattice L(K) of all subquasivarieties for some quasivariety K of algebraic systems. The current status of this problem, which is still open, is discussed. Various unsolved questions that are related to the Birkhoff-Maltsev problem are also considered, including ones that stem from the theory of propositional logics.Having whetted the reader's appetite in the preface to this special issue by claiming that much remains to be done in the theory of quasivarieties, we feel some responsibility to justify our claim. To do so, we will discuss the current status of the Birkhoff-Maltsev problem and consider open questions related to it.