2023
DOI: 10.1002/cbdv.202300234
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Xanchryones I−N, Six Unusual Phloroglucinol‐Amino Acid Hybrids from the Leaves of Xanthostemon chrysanthus

Abstract: Six new phloroglucinol derivatives, xanchryones IÀ N (1 -6), were isolated from the leaves of Xanthostemon chrysanthus. Compounds 1 -6 are unusual phloroglucinol-amino acid hybrids constructed through C 2 À N and OÀ C 1 ' bonds forming a peculiar oxazole ring. The structures and absolute configurations of compounds 1-6 were determined by MS, NMR, and single-crystal X-ray diffraction. Moreover, the anti-inflammatory and antibacterial activities of these compounds were evaluated.

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