Xanthogranulomatous Cholecystitis: A Retrospective Analysis of 36 Cases

Seo, Sang-Hyuk; Park, Jeong-Ik; Kim, Kwanghee; Choi, Chang-Soo; Choi, Yong Kee

doi:10.4174/jkss.2009.76.6.371

Cited by 6 publications

(2 citation statements)

References 14 publications

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“…No patient in the present study had findings that could have delayed a diagnosis of gallbladder tumor. Some studies have reported that radical surgery options may be considered in cases of high index of suspicion for malignancy, and that the results of frozen section examinations may be misleading [28,30]. In suspicious cases, a cholecystectomy specimen must be examined by the operating surgeon and sent for frozen section examination if deemed necessary after inspection and palpation [9].…”

Section: Discussionmentioning

confidence: 99%

“…Lee et al [ 27 ] compared the diagnostic performance of these 3 imaging modalities for XGC and found that although the performance of MRI was best, US performed better than CT. In a study by Seo et al [ 28 ], diffuse thickening of the gallbladder wall was observed in 66.6% of the patients, and a rate of gallbladder wall thickening was reported to be 66.6% and 87.7% in further studies [ 5 28 ]. In our study, 4 patients underwent a radical cholecystectomy, making an extended surgery rate of 5%.…”

Section: Discussionmentioning

confidence: 99%

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Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective

et al. 2020

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Xanthogranulomatous cholecystitis (XGC) was first described as benign and pseudotumor of the gallbladder in 1970 by Christensen and Ishak [1]. It was in 1981 when it was first described as a distinct pathological condition by Goodman and Ishak [2]. Xanthogranulomatosis is an idiopathic, rare process in which lipid-laden histiocytes are deposited at various locations in the body. Xanthogranulomatous inflammation occurs in various organs such as skin, kidney, retroperitoneum, intracranium, gastrointestinal tract, genital organs, and gallbladder [3,4]. XGC is an unusual form of chronic cholecystitis that may simulate malignancy radiologically and pathologically [5]. Many studies have been performed investigating whether there are imaging findings that might permit differentiation of XGC from cancer, such as diffuse gallbladder wall thickening, intramural "nodules" related to macrophage deposition, an intact gallbladder mucosa, and calculi [5,6]. The clinical picture can take the form of acute or chronic cholecystitis and may manifest with different symptoms

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective

et al. 2020

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A Case of Xanthogranulomatous Cholecystitis Decreased in Size after Steroid Treatment and Avoided Extended Resection

Kang¹,

Lee²,

Lee³

et al. 2015

Korean J Pancreas Biliary Tract

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Xanthogranulomatous cholecystitis is an uncommon destructive inflammatory disease with accumulation of lipid-laden macrophages, fibrous tissue, and inflammatory cells. It is often mistaken for gallbladder cancer due to diffuse wall thickening of gallbladder and infiltration into neighboring organs. And it is usually difficult to distinguish xanthogranulomatous cholecystitis from gallbladder cancer based on clinical, radiographic, or laboratory testing. Patients with xanthogranulomatous cholecystitis often undergo cholecystectomy to confirm the diagnosis, and to exclude gallbladder cancers. We report a case of 69-year-old woman with xanthogranulomatous cholecystitis who had been treated with steroid and avoided extended resection.

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Xanthogranulomatous Cholecystitis Mimicking Malignancy in Gallbladder

Park¹,

Cheon²,

Shim³

et al. 2018

Clin Ultrasound

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A 46-year-old female was referred for gallbladder (GB) mass and intrahepatic duct dilatation. There was no abdominal pain in the patient's examination, and there was no specific finding other than jaundice. Endoscopic retrograde cholangiopancreatography performed on the day after admission showed stenosis of the proximal bile duct and biopsy was performed and a biliary stent was inserted. Abdominal ultrasound and abdominal computed tomography showed that the GB wall was thickened diffusely and the GB wall structure was maintained, suggesting the possibility of xanthogranulomatous cholecystitis rather than GB cancer.

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Xanthogranulomatous Cholecystitis: A Retrospective Analysis of 36 Cases

Cited by 6 publications

References 14 publications

Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective

Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective

A Case of Xanthogranulomatous Cholecystitis Decreased in Size after Steroid Treatment and Avoided Extended Resection

Xanthogranulomatous Cholecystitis Mimicking Malignancy in Gallbladder

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