Xanthogranulomatous inflammation of myometrium with uterine perforation

Liao, Chi-Yuan; Chiu, Cheng-Hui; Luo, Fuh-Jinn

doi:10.1016/j.tjog.2012.12.003

Cited by 6 publications

(4 citation statements)

References 11 publications

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“…Xanthogranulomatous endometritis, also known as histiocytic endometritis or pseudoxanthomatous endometritis, is a rare disease characterized by chronic inflammation of the endometrium. To our knowledge, only 23 cases have been reported in English literature [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , of which only 7 cases contain imaging findings [4] , [5] , [6] , [7] , [8] , [9] , [10] . The incident age range is from 45 to 88 years.…”

Section: Discussionmentioning

confidence: 99%

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Xanthogranulomatous endometritis mimicking endometrial carcinoma: A case report and review of literature

Safneck

et al. 2019

Radiology Case Reports

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Xanthogranulomatous endometritis (XGE) is an extremely rare chronic inflammatory condition, which may be associated with endometrial hyperplasia, endometrial carcinoma, or cervical stenosis. Imaging features can be easily misdiagnosed as an aggressive malignancy. We present a case of XGE, which is the first case of XGE with serial multimodality imaging examinations, in addition to clinical, surgical and pathologic correlations. As such, this unique case illustrates the evolution of this rare disease.

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Section: Discussionmentioning

confidence: 99%

“…Based on prior case reports, the most common radiologic feature is heterogeneous cystic uterine mass (6 out of 8 cases) [4] , [5] , [6] , [7] , [8] , [9] , [10] . However, this was the first case that demonstrated a chronic, complex fluid collection in the endometrial canal prior to development of acute inflammation.…”

Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous endometritis mimicking endometrial carcinoma: A case report and review of literature

Safneck

et al. 2019

Radiology Case Reports

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“…XG inflammation rarely involves the myometrium and extends to the pelvis with uterine perforation ( Fig. 11 ) ( 49 ). Radiological features can easily lead to misdiagnosis of malignant tumors, and XG endometritis may be associated with endometrial cancer.…”

Section: Xanthogranulomatous Inflammation Of the Female Genital Tractmentioning

confidence: 99%

Imaging and Clinical Findings of Xanthogranulomatous Inflammatory Disease of Various Abdominal and Pelvic Organs: A Pictorial Essay

Lee,

Yang,

Kim

et al. 2024

J Korean Soc Radiol

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Xanthogranulomatous (XG) inflammatory disease is a rare benign disease involving various organs, including the gallbladder, bile duct, pancreas, spleen, stomach, small bowel, colon, appendix, kidney, adrenal gland, urachus, urinary bladder, retroperitoneum, and female genital organs. The imaging features of XG inflammatory disease are nonspecific, usually presenting as a heterogeneous solid or cystic mass. The disease may also extend to adjacent structures. Due to its aggressive nature, it is occasionally misdiagnosed as a malignant neoplasm. Herein, we review the radiological features and clinical manifestations of XG inflammatory diseases in various organs of the abdomen and pelvis.

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“…Benign tumors, spread of malignance from the endocervix, and endometrial cancer are usually associated with pyometra, and xanthogranulomatous inflammation is also reported in surgical specimens (16,17). The necrotic nature of the uterine tissue with pyometra sometimes requires frozen section examination.…”

Section: Case Presentationmentioning

confidence: 99%

Spontaneous perforation of pyometra: A rare cause of acute abdomen and sepsis

et al. 2018

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Pyometra, the accumulation of purulent material in the uterine cavity, is a rare gynecological condition whose etiology is impaired drainage of the uterine cavity. It is uncommon in premenopausal age and occurs mainly in older and postmenopausal women. Clinical signs of pyometra are vaginal discharge, postmenopausal bleeding, and lower abdominal pain. An 87-year-old woman was admitted to our emergency department with abdominal pain, fever, and vomiting. The results of physical examination revealed rebound tenderness and muscular rigidity in the lower abdomen. Ultrasonography demonstrated free fluid in the abdomen, and percutaneous aspiration revealed that this fluid was purulent. A computed tomography scan showed a large amount of free fluid in the abdominal cavity and a uterine myoma. The patient underwent emergency laparotomy due to acute abdomen. During the laparotomy, a 2x1 cm perforation was seen at the fundus of the uterus. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. A culture of the pus grew Escherichia coli. Histopathological examination revealed degenerative uterine myoma with no evidence of malignancy. Pathological results indicated myometrial suppurative inflammation along with neutrophilia and necrosis. Pyometra is a rare event; however, it must be considered when investigating acute abdomen etiology. Because pyometra involves abscess formation, drainage and evacuation of the uterine cavity while leaving a drain in the cavity and dilating the cervical canal is the main treatment protocol. In cases of perforation, hysterectomy is the treatment choice; however, with concomitant diseases in older patients, immediate surgery is related to important morbidity and mortality risks.

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Xanthogranulomatous inflammation of myometrium with uterine perforation

Cited by 6 publications

References 11 publications

Xanthogranulomatous endometritis mimicking endometrial carcinoma: A case report and review of literature

Xanthogranulomatous endometritis mimicking endometrial carcinoma: A case report and review of literature

Imaging and Clinical Findings of Xanthogranulomatous Inflammatory Disease of Various Abdominal and Pelvic Organs: A Pictorial Essay

Spontaneous perforation of pyometra: A rare cause of acute abdomen and sepsis

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