2002
DOI: 10.1055/s-2002-25085
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Xanthogranulomatous Pyelonephritis in Children: Diagnostic and Therapeutic Aspects

Abstract: XGP should be included in the differential diagnosis of all children presenting with perirenal or psoas abscess, renal mass and/or non-functioning kidney associated with/or without urolithiasis. Clinical awareness and a high index of suspicion is required to achieve the correct preoperative diagnosis and appropriate management. CT seems to be the most valuable imaging method for the diagnosis. We strongly recommend percutaneous drainage of the abscess and adjunctive antibiotic therapy prior to nephrectomy to a… Show more

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Cited by 57 publications
(94 citation statements)
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“…They recommend preliminary drainage, either surgically or percutaneously, of extrarenal abscesses prior to definitive surgical therapy. Two other groups concur with this recommendation and also emphasize the importance of adjunctive antibiotics prior to nephrectomy [29,30]. This two-stage approach was clearly necessary for our patient, given his extensive infection, fibrosis, and adhesions.…”
Section: Discussionsupporting
confidence: 64%
“…They recommend preliminary drainage, either surgically or percutaneously, of extrarenal abscesses prior to definitive surgical therapy. Two other groups concur with this recommendation and also emphasize the importance of adjunctive antibiotics prior to nephrectomy [29,30]. This two-stage approach was clearly necessary for our patient, given his extensive infection, fibrosis, and adhesions.…”
Section: Discussionsupporting
confidence: 64%
“…Total nephrectomy is the standard of treatment in diffuse forms. 23 In focal forms, first-line antibiotic therapy is advocated, with no recurrence reported in published studies. [24][25][26][27] Medical treatment avoids a decaying surgery and offers nephronsparing.…”
Section: Discussionmentioning
confidence: 99%
“…The differential diagnoses of renal mass associated with pyelo-calyceal involvement included Wilms' tumour [22,23], renal cell carcinoma [35], xanthogranulomatous pyelonephritis [1][2][3], malakoplakia [4][5][6], inflammatory pseudotumour of the renal pelvis [7][8][9], renal lymphoma [36], and fungal infection [10,11]. In our patient the lesion could not be identified preoperatively; hence, a needle biopsy was performed.…”
Section: Commentarymentioning
confidence: 93%
“…The renal scintigraphic patterns were independently interpreted by two senior nuclear medicine physicians who used standard criteria previously defined by Patel et al [15]. Diethyl triamine penta-acetic acid (DTPA) or mercapto-acetyl triglycerine (MAG 3) are more appropriate to evaluate renal function and flow, but, in accordance with some studies [3][4][5] and for our patient, renal scintigraphy with technetium-99 m-labelled DMSA was considered the imaging agent of choice for estimating the presence and extent of acute renal parenchymal changes.…”
Section: Commentarymentioning
confidence: 99%
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