1997
DOI: 10.1046/j.1365-2133.1997.6251567.x
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Xanthomas due to generalized oedema

Abstract: A unique case of normolipaemic eruptive xanthomas due to generalized oedema is described. We propose that in this patient eruptive xanthomas were caused by the capillary leak syndrome. The increased vascular permeability could be responsible for leakage of lipoproteins into the dermis with subsequent phagocytosis by histiocytic cells.

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Cited by 7 publications
(1 citation statement)
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“…We can hypothesize that, as a result of the break in the endothelial barrier, there is an increase in flux across the endothelial membrane of albumin and glycosaminoglycans such as hyaluronic acid. These observations can be compared with the case of a 48-year-old man having normolipaemic eruptive xanthomas during an attack of ISCLS [22]. The eruption was transient and consisted in multiple erythematous and infiltrated papulonodular lesions.…”
Section: Discussionmentioning
confidence: 91%
“…We can hypothesize that, as a result of the break in the endothelial barrier, there is an increase in flux across the endothelial membrane of albumin and glycosaminoglycans such as hyaluronic acid. These observations can be compared with the case of a 48-year-old man having normolipaemic eruptive xanthomas during an attack of ISCLS [22]. The eruption was transient and consisted in multiple erythematous and infiltrated papulonodular lesions.…”
Section: Discussionmentioning
confidence: 91%