Xanthomas of the stomach: a report of two cases

Andrejic, Bojana; Božanić, Snežana V.; Šolajić, Nenad; Djolai, Matilda; Levakov, Aleksandra M.

doi:10.17305/bjbms.2012.2512

Cited by 9 publications

(5 citation statements)

References 7 publications

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“…3,4,7 The diagnosis should be confirmed in order to eliminate the possibility of gastric malignancy. 8 In our case, xanthoma was diagnosed in an elderly male patient, where erythematous gastropathy was present. He had no history of diabetes mellitus, but the lipid status was not studied.…”

Section: Discussionmentioning

confidence: 70%

Gastric xanthelasma: case report

Almeida¹,

Fraga²,

Amaral³

et al. 2020

Int Surg J

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Xanthelasma, also known as Xanthoma or lipid island, is an uncommon gastrointestinal tract (GIT) tumor-like lesion and the stomach is its most frequent location in upper GI lesions, specifically in the gastric antrum, as a single lesion. The pathogenesis appears to be related to healing processes in response to tissue damage provoked by inflammation induced by Helicobacter pylori infection. Many studies have reported that successful H. pylori eradication helps prevent gastric cancer (GC) development. We present a case of a 77 years old patient that showed endoscopic diagnosis of erythematous gastropathy, a gastric antrum xanthelasma and H. Pylori infection. After confirmed H. pylori eradication, the lesion had complete regression. The successful eradication of H. pylori probably led to a total regression of the lesion. Gastric xanthelasma (GX) has been shown to be an independent predictive marker for early GC detection after H. pylori eradication. GX could be a useful marker for predicting the development of gastric cancer.

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Section: Discussionmentioning

confidence: 70%

Gastric xanthelasma: case report

Almeida¹,

Fraga²,

Amaral³

et al. 2020

Int Surg J

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“…It is more common in the elderly but can have a wide range of ages at presentation ( 14 , 15 ). Clinically, gastric xanthomas tend to be asymptomatic, and if symptomatic, they are typically related to coexisting pathology ( 1 ).…”

Section: Discussionmentioning

confidence: 99%

Gastric Xanthoma: A Rare Case Report

et al. 2023

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Xanthomas are characterized by the presence of foamy lipid-laden macrophages. The gastrointestinal tract is an uncommon site for xanthoma, with the stomach being the most favored location. They have been associated with various premalignant and malignant conditions of the stomach. We present a case of a 21-year-old female patient with dyspepsia of 4 months duration. Her lipid profile was mildly altered. On upper gastrointestinal endoscopy, multiple discrete yellow patches were found in the antrum, diagnosed as gastric xanthoma on microscopy. Various published literature has emphasized the frequent association of gastric xanthomas with gastritis, gastric atrophy, intestinal metaplasia, and gastric cancer. Hence, there is a necessity for early recognition, treatment of any coexistent pathology, and close clinical follow-up.

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“…Gastrointestinal xanthomas are seen primarily in older adults and are characterized by abundant lipid-containing histocytes present in the lamina propria ( 1 ). They are present most commonly in the stomach ( 2 ) and less often in the esophagus, duodenum, and colon. The occurrence of gastrointestinal xanthoma in children is rare but there has been a report of a gastric xanthoma ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

Pediatric Colonic Xanthomas, a Previously Unreported Colonoscopic Finding

Vanderhoof¹,

Goldsmith²,

Pauley³

et al. 2023

JPGN Reports

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Gastrointestinal xanthomas are benign, usually sessile, polypoid lesions occasionally incidentally seen in adults, usually in the stomach, but have not been reported in the large intestine in children. We identified xanthomas in the sigmoid colon of the 15-year-old girl confirmed histologically. Our findings suggest that colonic xanthomas may occur as an incidental finding in pediatric patients. They have a characteristic visual and histologic appearance but do not appear to be associated with any symptoms or illness and do not require follow-up.

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Xanthomas of the stomach: a report of two cases

Cited by 9 publications

References 7 publications

Gastric xanthelasma: case report

Gastric xanthelasma: case report

Gastric Xanthoma: A Rare Case Report

Pediatric Colonic Xanthomas, a Previously Unreported Colonoscopic Finding

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