Xanthomatous Biliary Cirrhosis in the Male

Spellberg, Mitchell A.; Gattas, Fred A.

doi:10.1016/s0016-5085(55)80028-5

Cited by 7 publications

(1 citation statement)

References 9 publications

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“…Sherlock (1959), nine years later in London, found that of 27 cases, four were Welsh, two Scottish and one Irish, ie, over 25 % were of Celtic origin. Most published series, eg, that of Foulk, Baggenstoss, and Butt (1959), mention a predilection of the disease for those of European descent, although cases in negroes are described (Ahrens, Payne, Kunkel, Eisenmenger, and Blondheim, 1950;Spellberg and Gattas, 1955) in the American literature.…”

Section: Discussionmentioning

confidence: 99%

The epidemiology of primary biliary cirrhosis: A survey of mortality in England and Wales

Hamlyn¹,

Sherlock²

1974

Gut

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SUMMARY Primary biliary cirrhosis is a rare disease in the general population. Estimates of its true incidence are difficult but since survival time is unaffected by treatment, mortality may reflect important regional and other variations. One hundred and sixty-five death certificates collected in England and Wales over the five-year period 1967-1971 were inspected and confirmed an overwhelming predilection for females. Deaths rose sharply at ages 50-54 in the latter with a peak of 4.1 million-' year-', with perhaps a secondary peak at ages 70-74. No relation of mortality with climate, altitude, soil type, annual temperature range, or occupation was found, although outside the UK a broad correlation exists with total cirrhosis deaths. There was a suggestive excess of deaths among married women. The greater frequency of deaths in the London area, a rise in mortality from country to urban areas, a fall-off in deaths from primary biliary cirrhosis in old age, and predominance for social class I suggest a simple relationship with standards of medical care or diagnosis.

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Section: Discussionmentioning

confidence: 99%