2019
DOI: 10.1038/s41393-019-0248-6
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Xenografting for disease modeling of intramedullary spinal cord tumors: a systematic review

Abstract: Study design Systematic review. Objectives The overall incidence of intramedullary spinal cord tumors (IMSCT) remains low and clinical trials or standardized treatment strategies are missing. Therefore, multiple animal-based xenograft models (AXM) have been developed to foster preclinical research efforts on IMSCT. We constructed a systematic literature review to summarize and compare all AXM for IMSCT, published until April 16, 2018. Methods The review was conducted using 4 independent research databases foll… Show more

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References 39 publications
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