Xenotransplantation Literature Update November–December, 2004

Baertschiger, Reto M.; Bühler, Léo H.

doi:10.1111/j.1399-3089.2005.00211.x

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Infectious Disease Risks1

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2007

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“…20 However, a study of long-term survivors of porcine pancreatic islet cell transplantation revealed no xenogeneic infections from PERV after nine years. 21 Both the scientific community and the lay public are keenly aware of the consequences arising from an unknown infection with a long latency period. We learned from the HIV/AIDS crisis that an infection could go unrecognized until an epidemic was already in progress.…”

Section: Infectious Disease Risksmentioning

confidence: 99%

Clinical Trials of Xenotransplantation: Waiver of the Right to Withdraw from a Clinical Trial Should Be Required

Spillman¹,

Sade²

2007

J. Law. Med. Ethics

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Xenotransplantation pits clinical research ethics against public health needs because recipients must undergo long-term, perhaps life-long, surveillance for infectious diseases. This surveillance requirement is effectively an abrogation of the right to withdraw from a clinical trial. Ulysses contracts, which are advance directives for future care, may be an ethical mechanism by which to balance public health needs against limitation of individual rights.

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Section: Infectious Disease Risksmentioning

confidence: 99%