Xerostomia: Diagnosis and treatment

Navazesh, Mahvash; Ship, Irwin I.

doi:10.1016/s0196-0709(83)80072-6

Cited by 71 publications

(51 citation statements)

References 40 publications

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“…Reasons for this relationship between complaints and different swallowing results cannot be deduced from this study. However, we may speculate that clinical measures such as these have important therapeutic implications [5,13,14] and ultimately may even yield critical perspectives regarding differences among patients with primary SS [8][9][10] and/or prediction of changes in the course of this autoimmunc disease.…”

Section: Discussionmentioning

confidence: 99%

Objective measures of swallowing in patients with primary Sjogren's syndrome

et al. 1989

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Primary Sjogren's syndrome (SS) is an autoimmune disorder primarily affecting salivary and lacrimal glands. Durational measures of the oral phase of swallowing were obtained on 34 patients with primary SS and 34 age-matched controls from analyses of ultrasound scans. Two conditions were examined: a basal (BA) swallow (only endogeneous secretions present in the subjects' mouths) and a 10 ml water bolus (WB) swallow. The patients with SS produced swallowing durations significantly longer (p less than 0.05) than those of the controls for each of the two conditions. Moreover, unlike normals, over 40% of the patients with SS produced WB swallows that were longer than their BA swallows. For further analyses, patients with SS were classified into two groups based on the difference in duration between their BA and WB swallows. These two groups differed from each other on clinical evaluations of oral motor function and presenting complaints. No significant differences were found between these two groups for salivary function or immunologic profile. These findings support the hypothesis that dysphagia can result from conditions leading to salivary gland dysfunction and document the need for the assessment of swallowing function in patients with Sjogren's syndrome.

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Section: Discussionmentioning

confidence: 99%

Objective measures of swallowing in patients with primary Sjogren's syndrome

et al. 1989

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“…An increased incidence of coronal and root caries has long been a recognised consequence of hyposalivation [79]. Xerostomia is also characterised by alterations in the normal oral microflora, with an increase in the proportion of anaerobic organisms; such changes may, in part, be attributable to the absence of dissolved oxygen normally present in saliva [63]. There is, in addition, an approximately inverse relationship between salivary flow and the occurrence of Candida albicans [49].…”

Section: Complications Of Xerostomiamentioning

confidence: 99%

Xerostomia: aetiology and management in cancer patients

Holmes

1998

Support Care Cancer

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Although oral complications are common sequelae of cancer/cancer treatment, only sporadic research is published in the literature. It is clear that 'routine' oral hygiene measures are inadequate; a little time and effort may, however, reduce oral discomfort. This is particularly true in the case of xerostomia, which is often thought to be a relatively minor symptom with few deleterious effects. Many patients, however, find xerostomia a significant cause of distress, and for this reason alone, health care professionals require knowledge and appreciation of the pathology and aetiology of the condition and approaches to its management. This paper reviews the physiology of salivation and the aetiology of xerostomia and considers the ways in which the condition can be managed.

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“…There are two possibilities for what this interaction might have indicated: (1) group differences on this measure were present for only certain bolus types, or (2) there were significant differences between bolus types within one group but not within the other group. To further clarify this interaction, post-hoc analysis was performed using paired-sample t tests with a Bonferroni correction first to compare the two groups (patients with controls) by bolus type and second to compare the different bolus types within each separate group.…”

Section: Interaction Effects For Temporal Measuresmentioning

confidence: 99%

“…Hyposalivation occurs when there is a reduction in the amount of saliva produced by the salivary glands (a decreased salivary flow rate). Xerostomia, the subjective perception of dry mouth, usually accompanies hyposalivation [1,2] but may occur without a reduction in salivary flow rate as well [3,4]. Swallowing often becomes difficult for those with hyposalivation and/or xerostomia [1].…”

mentioning

confidence: 99%

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Effects of Reduced Saliva Production on Swallowing in Patients with Sjogren’s Syndrome

Rogus-Pulia

Logemann

2010

Dysphagia

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This study aimed to further characterize the nature of swallowing dysfunction in patients with Sjogren's syndrome (SS). Subjects filled out a perception of swallow function form. Measures of stimulated salivary flow rate were also taken, and videofluoroscopic evaluation of swallowing was completed. The amount of saliva produced by patients with SS was significantly less than that produced by normal age-matched controls, and these patients perceived their swallowing to be impaired. Few statistically significant differences were found between the SS group and normal age-matched controls on temporal measures of swallowing, and 96% of swallows in the SS group were judged to be functional. There was no correlation between perception of swallowing and amount of saliva produced. No strong correlations were found between temporal measures of swallowing and salivary flow rate. Results indicated that patients with SS tend to perceive their swallowing to be worse than physiologic swallowing measures indicate. The decreased saliva production in these patients does not appear to be the cause of their perceived swallowing difficulty but may affect their sensory judgment of swallow function. Future studies will focus on how quality of saliva affects swallowing in these patients.

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Xerostomia: Diagnosis and treatment

Cited by 71 publications

References 40 publications

Objective measures of swallowing in patients with primary Sjogren's syndrome

Objective measures of swallowing in patients with primary Sjogren's syndrome

Xerostomia: aetiology and management in cancer patients

Effects of Reduced Saliva Production on Swallowing in Patients with Sjogren’s Syndrome

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