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Abstract

Cancer is a major health problem; almost thought -out the world. Herbal medicines have a vital role in the prevention and treatment of cancer. The present study, the in vitro anticancer activity of Calophyllum inophyllum ethanolic leaf extract was evaluated in MCF-7 Breast cancer cell lines. Anticancer activity was evaluated with MTT standard colorimetric assay against MCF-7 cells with IC50 value of 120µg/mL. The biologically active metabolites were identified and quantified by a GC-MS method shows presence of 11 different bioactive compounds. The cytotoxic effect was found to be concentration dependent. Increased concentration of the leaf extract showed increased cytotoxicity.

Anti-proliferative and apoptosis inducing activity of Calophyllum inophyllum L. oil extracts on C6 glioma cell line

“…Considering its wide biological activities C. inophyllum has a great potential to be used in pharmaceutical development, especially for use in cancer treatment. However, there are limited numbers of studies in the literature that have investigated the potential use of C. inophyllum extracts in cancer treatment (Hsieh et al, 2018;Jaikumar et al, 2016;Shanmugapriya et al, 2017).…”