XLV.—Optical activation of racemic acid by l-malic acid

Abstract

WITH reference to the existence of optically active substances in nature, van't Hoff predicted the possibility of their formation '' bei unsymmetrischen Versuchsbedingungen, bei Umwandlungen z.B. UNIVEESITY COLLEGE, DUNDEE. UNIVERSITY OF ST. ANDREWS.

Resolution of Optical Isomers by Crystallization Procedures.

“…11. Alkali Metal Hydrogen dl-Tartrates It was found that resolution occurred to a very small degree when racemic sodium, potassium, rubidium or cesium hydrogen (ZZ-tartrate was crystallized from a solution of either dor Z-malic acid (68,69,70). Since no seed crystals were added, resolution presumably occurred as a result of the asymmetric influence of the medium, that is, as a result of the difference in solubility of the d-and Z-tartrates in the optically active solutions of malic acid.…”