Y-Maze memory task in zebrafish (Danio rerio): The role of glutamatergic and cholinergic systems on the acquisition and consolidation periods

The Role of Mental and Physical Activities against Development of Alzheimer ’s Disease in Socialized and Isolated Rats

“…Also, AD isolated group showed a significant decrease in swimming time to 67.6% with respect to their corresponding control group. It was found that socialized group showed a significant decrease in swimming time to 46.1% in the second week as compared to the first week. Also, it was found that social isolation for a long period caused a significant decrease in swimming time to 55.03% in the second week as compared to the first week.…”

“…Rats preferred to investigate the new arm of the maze rather than returning to the arm that was previously visited. Different brain parts as hippocampus, basal forebrain, septum and prefrontal cortex were involved in Y-maze task [46,47]. It is evident that rat must remember which arm it had entered on a previous occasion to enable the alternation of its choice on the following trial.…”

Spontaneous alternation behavior in larval zebrafish

“…Adult zebrafish perform well in multiple memory-related experiments including olfactory conditioning (Braubach et al, 2009), spatial alternation (Cognato et al, 2012), and associative (Sison and Gerlai, 2010;Valente et al, 2012) and non-associative (Tran and Gerlai, 2014) learning. Mnestic studies using larval zebrafish, in contrast, have only commenced recently (Roberts et al, 2013).…”

Does serotonin-modulating anticonsolidation protein (SMAP) influence the choice of turning direction in carps, Cyprinus carpio, in a T-maze?

“…Fish can use diverse sources of spatial information from different sensory modalities and rely on a variety of spatial strategies that are parallel to those described in land vertebrates. '' In order to investigate the mechanisms of orientation in fish and clarify the role of learning and memory in these mechanisms, various experimental devices have been used, depending on the objectives of the particular study: T-mazes (D'Amico et al 2015), Y-mazes (Cognato et al 2012), plus-mazes (Gaikwad et al 2011;Creson et al 2003), meander mazes (Walton and Moller 2010) as well as other installations, where the elements of the landscape similar to the natural conditions of the fish's habitat were created (Burns and Rodd 2008). While developing an experimental procedure, researchers should take into account the species-specific characteristics of biology and behavior of fish such as the structure of sensory organs, ways of processing of sensory information, patterns of locomotion, interaction with other individuals.…”

“…In recent decades, molecular mechanisms of long-term memory formation in fish have attracted increasing attention of researchers. In particular, the involvement of cholinergic and glutamatergic neurotransmitter systems in the processes of learning and memory in Danio rerio has been revealed (Cognato et al 2012). In addition, the negative effect of a novel serotonin-modulating anticonsolidation protein (SMAP) on the consolidation of memory traces in mammals Mekhtiev 2010, 2012) and fish Mekhtiev 2012, 2014) has been found.…”