We point out that the global symmetries of the Yang-Mills theory in the Landau gauge support existence of variables similar to director fields in liquid crystal systems. We discuss two different types of the liquid crystal variables associated with the group of global Euclidean rotations and with a residual global group of color transformations. These global symmetries allow to identify various topological defects which resemble, in particular, vortex-like disclination defects and monopole-like objects in nematic liquid crystals. We suggest that the deconfinement phase transition in the Yang-Mills theory may be associated with a phase transition in a liquid crystal.