Year in review: pediatric allergy and asthma, excluding food allergy

Hauptman, Marissa; Phipatanakul, Wanda

doi:10.1016/j.anai.2015.01.002

Cited by 6 publications

(6 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For various reasons, including air pollution and climate change, the prevalence of allergic disease in the USA has risen dramatically since the mid‐20 th century. Today, asthma is the most common chronic childhood disease, affecting almost 9.6% of American children; it is also the leading cause of school absenteeism and hospitalization . In the United States, 20% of the population are sensitized to Lolium allergens, the highest rates being recorded in the Western states.…”

Section: Clinical Data and Sensitizationmentioning

confidence: 99%

Poaceae pollen as the leading aeroallergen worldwide: A review

Garcı́a-Mozo

2017

Allergy

147

View full text Add to dashboard Cite

The Poaceae family comprises over 12 000 wind-pollinated species, which release large amounts of pollen into the atmosphere. Poaceae pollen is currently regarded as the leading airborne biological pollutant and the chief cause of pollen allergy worldwide. Sensitization rates vary by country, and those variations are reviewed here. Grass pollen allergens are grouped according to their protein structure and function. In Poaceae, although species belonging to different subfamilies are characterized by distinct allergen subsets, there is a considerable degree of cross-reactivity between many species. Cross-reactivity between grass pollen protein and fresh fruit pan-allergens is associated with the appearance of food allergies. The additional influence of urban pollution may prompt a more severe immunological response.The timing and the intensity of the pollen season are governed by species genetics, but plant phenology is also influenced by climate; as a result, climate changes may affect airborne pollen concentrations. This article reviews the findings of worldwide research which has highlighted the major impact of climate change on plant phenology and also on the prevalence and severity of allergic disease.

show abstract

Section: Clinical Data and Sensitizationmentioning

confidence: 99%

Poaceae pollen as the leading aeroallergen worldwide: A review

Garcı́a-Mozo

2017

Allergy

147

View full text Add to dashboard Cite

show abstract

“…Children have immature lungs and airways which are more susceptible to inflammation than their adult counterparts; children between 6 and 18 years, as compared with adults, are at high risk for emergency hospitalization for asthma [ 18 ]. Asthma continues to pose a substantial burden to child and adult health, with approximately 9.6% of children in the United States living with the disease [ 19 , 20 ]. Asthma appears to disproportionately affect children from minority and impoverished communities [ 19 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

“…Asthma continues to pose a substantial burden to child and adult health, with approximately 9.6% of children in the United States living with the disease [ 19 , 20 ]. Asthma appears to disproportionately affect children from minority and impoverished communities [ 19 , 21 ]. A review of the scientific literature, covering periods of 2006–2009, explored the relationship between outdoor air pollution and asthma in children [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Outdoor Environment and Pediatric Asthma: An Update on the Evidence from North America

Pollock

Shi

Gimbel

2017

Canadian Respiratory Journal

View full text Add to dashboard Cite

Introduction. The evidence about the association between asthma and outdoor environmental factors has been inadequate for certain allergens. Even less is known about how these associations vary across seasons and climate regions. We reviewed recent literature from North America for research related to outdoor environmental factors and pediatric asthma, with attention to spatial-temporal variations of these associations. Method. We included indexed literature between years 2010 and 2015 on outdoor environmental factors and pediatric asthma, by searching PubMed. Results. Our search resulted in 33 manuscripts. Studies about the link between pediatric asthma and traffic-related air pollutants (TRAP) consistently confirmed the correlation between TRAP and asthma. For general air pollution, the roles of PM2.5 and CO were consistent across studies. The link between asthma and O3 varied across seasons. Regional variation exists in the role of SO2. The impact of pollen was consistent across seasons, whereas the role of polycyclic aromatic hydrocarbon was less consistent. Discussion. Recent studies strengthened the evidence about the roles of PM2.5, TRAP, CO, and pollen in asthma, while the evidence for roles of PM10-2.5, PM10, O3, NO2, SO2, and polycyclic aromatic hydrocarbon in asthma was less consistent. Spatial-temporal details of the environment are needed in future studies of asthma and environment.

show abstract

“…Otherwise, Hauptman et al (2015) is a systematic review analyzing the epidemiology and evidence of known or proposed mechanisms of environmental, chemical, infectious, and perinatal exposures that relate to the development of pediatric allergy and asthma. The new evidence explores the effects of high- and low-molecular-weight phthalates, such as pesticides, dichlorophenols, and broad-spectrum antimicrobials, of their impact on the development of asthma [ 24 ].…”

Section: Resultsmentioning

confidence: 99%

Effect of Gestational Pesticide Exposure on the Child’s Respiratory System: A Narrative Review

Ventura-Miranda

Medina

Guillén-Romera

et al. 2022

IJERPH

View full text Add to dashboard Cite

Background: In recent years, concern has arisen worldwide about the potential adverse effects that could result from early-life exposure to pesticides. Asthma, bronchitis, and persistent cough in children have been linked to gestational exposure to pesticides. The respiratory effects of gestational exposure to pesticides are controversial. The aim of this study was to determine the relationship between pesticide exposure in pregnant women and its effect on the respiratory system of their children. Methods: A narrative review was carried out by means of a search in the main databases. Results: Findings of studies confirmed the effects of pesticides on the child’s health. These substances cross the placenta and become transmitters of exposure to the individual at the most sensitive stage of her development. Conclusions: Chronic exposure to pesticides in fetuses is associated with chronic respiratory symptoms and disease.

show abstract

Year in review: pediatric allergy and asthma, excluding food allergy

Cited by 6 publications

References 28 publications

Poaceae pollen as the leading aeroallergen worldwide: A review

Poaceae pollen as the leading aeroallergen worldwide: A review

Outdoor Environment and Pediatric Asthma: An Update on the Evidence from North America

Effect of Gestational Pesticide Exposure on the Child’s Respiratory System: A Narrative Review

Contact Info

Product

Resources

About