Yersinia enterocolitica infection among children aged less than 12 years: a case–control study

Qouqa, Iyad A. El; Jarou, Mahmoud A. El; Samaha, Ahmed S. Abu; Afifi, Ahmed S. Al; Jarousha, Abdel Moati Kh. Al

doi:10.1016/j.ijid.2010.09.010

Cited by 25 publications

(17 citation statements)

References 27 publications

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“…enterocolitica isolated from human stools greatly varies depending on the study, the country, the patients recruited, and the isolation procedures. For instance it was reported to be 0.19% (82/41,848 patients) in Finland [61], 4% (24/600 patients) in Palestine [62], 0.74% (36/4,841 patients) in the USA [63], 0.16% (6/3,784 patients) in UK [64], 0.6% (46/7,090 patients) in Crete [65], 2.46% (267/10,838 patients) in Belgium [66], 0.13% (3/2250 patients) in Canada [67], 0.42% (4/956 patients) in China [68], or 0% in Ireland (0/1,189 patients) [69] and the Netherlands (0/857 patients) [70]. In the Abidjan district, the isolation rate was 0.46% (2/427 patients), and therefore equivalent to or higher than those reported in several European countries (Finland, UK, Ireland and the Netherlands), Canada and China.…”

Section: Discussionmentioning

confidence: 99%

Yersinia enterocolitica, a Neglected Cause of Human Enteric Infections in Côte d’Ivoire

et al. 2017

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BackgroundEnteropathogenic Yersinia circulate in the pig reservoir and are the third bacterial cause of human gastrointestinal infections in Europe. In West Africa, reports of human yersiniosis are rare. This study was conducted to determine whether pathogenic Yersinia are circulating in pig farms and are responsible for human infections in the Abidjan District.Methodology/Principal findingsFrom June 2012 to December 2013, pig feces were collected monthly in 41 swine farms of the Abidjan district. Of the 781 samples collected, 19 Yersinia strains were isolated in 3 farms: 7 non-pathogenic Yersinia intermedia and 12 pathogenic Yersinia enterocolitica bioserotype 4/O:3. Farm animals other than pigs and wild animals were not found infected. Furthermore, 2 Y. enterocolitica 4/O:3 strains were isolated from 426 fecal samples of patients with digestive disorders. All 14 Y. enterocolitica strains shared the same PFGE and MLVA profile, indicating their close genetic relationship. However, while 6 of them displayed the usual phage type VIII, the other 8 had the highly infrequent phage type XI. Whole genome sequencing and SNP analysis of individual colonies revealed that phage type XI strains had unusually high rates of mutations. These strains displayed a hypermutator phenotype that was attributable to a large deletion in the mutS gene involved in DNA mismatch repair.Conclusions/SignificanceThis study demonstrates that pathogenic Y. enterocolitica circulate in the pig reservoir in Côte d'Ivoire and cause human infections with a prevalence comparable to that of many developed countries. The paucity of reports of yersiniosis in West Africa is most likely attributable to a lack of active detection rather than to an absence of the microorganism. The identification of hypermutator strains in pigs and humans is of concern as these strains can rapidly acquire selective advantages that may increase their fitness, pathogenicity or resistance to commonly used treatments.

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Section: Discussionmentioning

confidence: 99%

Yersinia enterocolitica, a Neglected Cause of Human Enteric Infections in Côte d’Ivoire

et al. 2017

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“…Of these, 87 relevant original articles were identified and classified under 11 thematic areas. Only nine studies (15)(16)(17)(18)(19)(20)(21)(22)(23) examined the association between water quality and health effects (Table 1). In the literature describing contaminants in the water supply in the Gaza Strip, salt was the most notable cause of decreased water quality, followed by nitrates and infectious organisms.…”

Section: Review Of Literature and Waterquality Guidelinesmentioning

confidence: 99%

Water usage in the Gaza Strip: recommendations from a literature review and consultations with experts

MacDonald

Herrador

Hyllestad

et al. 2016

East Mediterr Health J

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Water quality in the Gaza Strip has been severely compromised due to increasing salinity, contamination with pollutants, and lack of adequate treatment options. To provide the population of the Gaza Strip with advice on how to mitigate health risks from water we developed recommendations on using water from different sources for different purposes (such as for consumption, hygiene, amenities, and irrigation) based on a literature review and consultation with experts. Specific advice was developed for several vulnerable groups, including infants, children, pregnant or lactating women, and elderly people. The recommendations are inherently limited, as it is unacceptable to recommend consuming water that is of substandard quality. However, pending long-term solutions, information can be targeted to vulnerable groups to ensure that exposure to the most harmful contaminants is avoided. The implementation of these recommendations may require information campaigns to assist the population in differentiating water from different sources for different uses.

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“…Y. enterocolitica is sensitive to meropenem, ceftriaxone, ciprofloxacin, ceftazidime and amikacin, while is resistant to ampicillin (61).…”

Section: Bacterial Infectionmentioning

confidence: 99%

Treatment of Acute Diarrhoea: Past and Now

Caramia¹,

Silvi²,

Verdenelli³

et al. 2015

Int J Enteric Pathog

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Context: Since ancient times diarrhoea has been a highly fatal disease and even today diarrhoea, the topic of this review, is a problem affecting millions of people around the world despite the efforts of governments and professionals from the medical area. Worldwide the most common cause of children's death is diarrhoea. Evidence Acquisition: Diarrhoea disorders generally appear with watery stools, sometimes mixed with blood, accompanied by abdominal pain, vomiting and fever. The symptoms depend on the content and distribution of body fluid, daily water requirements and physiological water loss in connection with age through sweating, urination and breathing, the degree of fluid and electrolyte loss in the liquid stool. Results: Several effective interventions have been introduced as part of diarrhoea management in the last two decades such as oral rehydration solution, zinc supplementation, vitamin A supplementation and oral administration of antibiotics and vaccines. To reduce the mortality rate, control of safe drinking water, good sanitation and vaccination against typhoid and cholera are recommended, especially in high-risk populations. Probiotics have been proposed, after more than a half of century, as additional therapy in the treatment of acute diarrhoea. Several probiotic strains showed benefit in meta-analyses of randomised controlled trials. Conclusions: Due to the high level of evidence available, the term "oral bacteriotherapy", used for decades in the prevention and therapy of gastroenteritis in the growing age and adults, has expanded, but probiotics are acquiring significant scientific value based on the results from human trials. The future of probiotics depends on further explanation/elucidation of basic mechanisms, allowing scientists and physicians to maximize their health benefits.

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Yersinia enterocolitica infection among children aged less than 12 years: a case–control study

Abstract: This study demonstrated that Y. enterocolitica occurs sporadically in children, with a predominance of serotypes O:3 and O:9. Furthermore malnutrition was identified as the main risk factor for yersiniosis.

Cited by 25 publications

References 27 publications

Yersinia enterocolitica, a Neglected Cause of Human Enteric Infections in Côte d’Ivoire

Yersinia enterocolitica, a Neglected Cause of Human Enteric Infections in Côte d’Ivoire

Water usage in the Gaza Strip: recommendations from a literature review and consultations with experts

Treatment of Acute Diarrhoea: Past and Now

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