Yersinia pestis from Natural Foci

Кутырев, Владимир; Protsenko, Oľga A.; Smirnov, G. B.; Boolgakova, E. G.; Куклева, Л. М.; Зудина, И. В.; Vidyaeva, N. A.; Koozmichenko, Inna

doi:10.1007/0-306-48416-1_59

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…Potentially different‐sized chromosomal deletions have been detected in some Y. pestis strains (Fetherston et al, ); these deletion mutants are not the specific pgm deletion exempted from Select Agent regulations. While Δ pgm mutations are readily isolated in epidemic strains of Y. pestis , this specific deletion may not occur in endemic strains (less virulent or avirulent in humans; Kutyrev et al, ; S. Bearden et al, unpub. observ.…”

Section: Commentarymentioning

confidence: 99%

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Isolation and Confirmation of Yersinia pestis Mutants Exempt from Select Agent Regulations

Perry

Bearden

2008

CP Microbiology

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This unit describes protocols for Yersinia pestis to confirm plasmid profiles, construct and confirm a Δpgm mutation, and cure the low‐calcium response (Lcr) plasmid encoding a type III secretion system (TTSS). Strains lacking either the chromosomal pgm locus or the Lcr plasmid can be safely studied under BSL‐2 conditions and are exempt from Select Agent regulations in the U.S. Curr. Protoc. Microbiol. 11:5B.2.1‐5B.2.12. © 2008 by John Wiley & Sons, Inc.

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Section: Commentarymentioning

confidence: 99%

“…Current Protocols in Microbiology Supplement 11 specific deletion may not occur in endemic strains (less virulent or avirulent in humans; Kutyrev et al, 2003;S. Bearden et al, unpub.…”

Section: B211mentioning

confidence: 99%

Isolation and Confirmation of Yersinia pestis Mutants Exempt from Select Agent Regulations

Perry

Bearden

2008

CP Microbiology

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“…степановым (1975) в основу классификации, выделявшей пять подвидов чумного микроба [7]. в качестве дополнительных тестов для дифференциации подвидов предложены также тесты наличия изоцитратлиазной активности, чувствительности к фагу м1, особенности плазмидного состава [8]. и.л.…”

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Historical and Modern Classifications of the Plague Agent

Eroshenko

Куклева

Кутырев

2023

Problemy Osobo Opasnykh Infektsii

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The review presents the data on domestic and foreign phenotypic classifications of Yersinia pestis strains developed in the XX century; genetic classifications of the XXI century; as well as on the genealogy of ancient strains of the plague microbe, reconstructed using paleogenomic technologies. Since the discovery of the plague agent in 1894, many classifications were created that corresponded to the level of development of microbiology at that time. The intraspecific classification schemes of the XX century were based on three principles: phenotypic differences between strains, features of the species composition of carriers, and geographical affiliation. With the development of molecular microbiology early on in the XXI century, a genetic nomenclature of the branches of the pathogen evolution was developed and a number of classifications based on the analysis of the population structure of Y. pestis were created. Through the prism of the genetic diversity of Y. pestis strains from natural plague foci in Russia, near and far abroad countries, an improved classification with a division into seven subspecies has been developed: pestis, tibetica, caucasica, qinghaica, angolica, central asiatica, ulegeica, which allocates the subspecies according to the phylogenetic principle and epidemic significance. With the advancements in paleomicrobiology, prehistoric lineages of evolution have been included in the genealogy of Y. pestis, which expand the data on the intraspecific diversity of the plague microbe.

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Prospects for the Synthesis of Ecological and Molecular-Genetic Approaches to the Problem of the Speciation of the Plague Microbe Yersinia pestis

Suntsov

2020

Biol Bull Rev

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Yersinia pestis from Natural Foci

Cited by 3 publications

References 9 publications

Isolation and Confirmation of Yersinia pestis Mutants Exempt from Select Agent Regulations

Isolation and Confirmation of Yersinia pestis Mutants Exempt from Select Agent Regulations

Historical and Modern Classifications of the Plague Agent

Prospects for the Synthesis of Ecological and Molecular-Genetic Approaches to the Problem of the Speciation of the Plague Microbe Yersinia pestis

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