W heat is a winter cereal crop which requires relatively low temperatures ranging from 12 to 22º C and these temperatures are considered optimum for its reproductive development (Farooq et al., 2011). This crop is considered amongst the most important crops in Pakistan because of its contribution of 1.6% and 8.9% in GDP and value added in agriculture of our homeland being cultivated on 8.74 million hectares up to 2019 yielding 25.195 million tonnes (GOP, 2019). For our country, this Abstract | A fast change in the climate has perplexed the world by creating drought and its related issues. In this way, plenty of hexaploid wheat is influenced in our Pakistan. For combating this situation, research was carried out on sixteen bread wheat genotypes to see the effect of water stress at the experimental field, NIA, Tandojam in an RCBD with factorial arrangement of three treatments i.e. T 1 (zero irrigation), T 2 (two irrigations), T 3 (four irrigations) during Rabi season, 2016-2017. The ANOVA results exposed significant differences among genotypes as well as treatments for most of the attributes, however genotypes x treatment was also significant for several characters. Among the treatments, T 3 (four irrigation) recorded higher mean perform then T 2 (two irrigation) and T 1 (zero irrigation) which showed that different irrigation regimes caused significantly impact on all the traits. Among the genotypes, V3-10-34 showed minimum reduction in spike length, spikelets per spike, grains per spike, seed index, grain yield per plant and harvest index. The genotype, V2-10-15 manifested minimum decrease for days to 75% maturity and spikelets per spike at zero irrigation and two irrigations. C7-98-4 gave minimum decrease for flag leaf area and V2-10-3 caused smaller amount of reduction for biological yield plant -1 at zero irrigation and two irrigations. The genotypes like V3-10-34, V2-10-15, C7-98-4 and V2-10-3 could be recommended for the water deficiency areas of farmers.