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Background Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Caffeine, as the most widely consumed psychoactive substance, has been suggested to have potential effects on the clinical course and disability levels of MS patients. This study aimed to review the current evidence on the effects of coffee/caffeine in patients with MS. Methods This study followed the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis and PRISMA 2020 statement. Clinical evidence regarding the effects of caffeine/coffee in MS patients was considered. A systematic search was performed in PubMed, Scopus, Web of Science, and Embase in October 2023, and updated via handsearching in March 2024. JBI's critical appraisal tools were utilized to scrutinize the risk of bias. Results Out of 297 screened records, eight studies were eventually found to meet our inclusion criteria. The sample size of the studies varied between 12 and 1372 and the study designs were retrospective cohort, RCT, single-blind crossover trial, single-arm pilot study (each one study), and cross-sectional (four studies). No significant association between the level of disability and coffee/caffeine intake has been reported, although it was reported to be associated with cognitive improvements. Discussion Evidence indicates an association between coffee/caffeine consumption, and improved cognitive outcomes in patients with MS, while there is no considerable relationship with the disease disability. Considering the limitations of the evidence, such as the small number of studies, and great diversity in study designs, the findings of this study should translate to clinical practice with caution.
Background Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Caffeine, as the most widely consumed psychoactive substance, has been suggested to have potential effects on the clinical course and disability levels of MS patients. This study aimed to review the current evidence on the effects of coffee/caffeine in patients with MS. Methods This study followed the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis and PRISMA 2020 statement. Clinical evidence regarding the effects of caffeine/coffee in MS patients was considered. A systematic search was performed in PubMed, Scopus, Web of Science, and Embase in October 2023, and updated via handsearching in March 2024. JBI's critical appraisal tools were utilized to scrutinize the risk of bias. Results Out of 297 screened records, eight studies were eventually found to meet our inclusion criteria. The sample size of the studies varied between 12 and 1372 and the study designs were retrospective cohort, RCT, single-blind crossover trial, single-arm pilot study (each one study), and cross-sectional (four studies). No significant association between the level of disability and coffee/caffeine intake has been reported, although it was reported to be associated with cognitive improvements. Discussion Evidence indicates an association between coffee/caffeine consumption, and improved cognitive outcomes in patients with MS, while there is no considerable relationship with the disease disability. Considering the limitations of the evidence, such as the small number of studies, and great diversity in study designs, the findings of this study should translate to clinical practice with caution.
Nörolojik Hastalıklarda Yoganın Kullanımı ve Sağlığa Etkisi Öz Yoga, fiziksel egzersizleri, nefes alma tekniklerini, meditasyonu ve sağlıklı bir yaşam tarzını birleştiren ve Hint felsefesine dayanan eski bir yöntemdir. Yoga, sistemlerimizi dengelemek için zihni (meditasyon) ve bedeni (egzersizler) kullanan manevi bir uygulamadır. Zihnin duyguları ve bedeni etkileme yeteneklerini araştırır. Bu nedenle Ulusal Tamamlayıcı Alternatif Tıp Merkezi (The National Center for Complementary Alternative Medicine) yogayı zihin-beden tıbbı olarak sınıflandırır. Zihin-beden terapileri beyin, zihin, beden ve davranış arasındaki ilişkilere ve bunların sağlık ve hastalık üzerindeki etkilerine odaklanır. Yoga uygulaması da sağlık ve esenliği iyileştirmek için bireyin fiziksel, zihinsel ve ruhsal bileşenlerini bütünleştirir. Bu nedenle yoga bir bilim olduğu kadar ayrıca sağlıklı yaşam sanatıdır. Sağlığın teşviki, hastalıkların önlenmesi ve nörolojik bozukluklar için olası bir tedavi yöntemi olarak yaygın bir şekilde kullanılmaktadır. Multiple skleroz, parkinson, demans, epilepsi, alzheimer hastalığı, baş ağrıları ve inme gibi çeşitli nörolojik hastalıklardaki etkilerini araştıran çalışmalarda yoga pratiğinin hastalık semptomları, denge, güç, esneklik, bilişsel durum, depresyon, anksiyete ve yaşam kalitesi üzerinde etkili olduğu bildirilmiştir. Yoganın nörolojik hastalıklardaki sağlık üzerine olumlu etkileri göz önünde bulundurulduğunda; hastalar için makul derecede güvenli, uygun maliyetli, uygulanabilir ve umut verici bir yöntem olduğu söylenebilir. Hastaların eğitiminde en önemli rolü oynayan sağlık profesyonelleri olarak hemşirelerin, nörolojik hastalıklardaki semptomları yönetebilecek ve kontrol edebilecek mevcut tamamlayıcı ve bütünleştirici yöntemler hakkında bilgilendirilmeleri çok önemlidir. Ayrıca hemşireler, hastalara özellikle ileri düzey yoga uygulamaları yapılırken hastaların istenmeyen etkilerden kaçınmalarını sağlamak için gereken bilgilendirmeyi ve özeni göstermeleri gereklidir. Bu derlemenin amacı, yoganın nörolojik hastalıklardaki kullanım durumunu değerlendirmek ve sağlık üzerindeki etkisini incelemektir. Anahtar Kelimeler: Hemşirelik, nöroloji, yoga. Use of Yoga in Neurological Diseases and Its Effect on Health Abstract Yoga is an ancient method based on Indian philosophy that combines physical exercises, breathing techniques, meditation and a healthy lifestyle. Yoga is a spiritual practice that uses the mind (meditation) and body (exercises) to balance our systems. It explores the mind's ability to influence emotions and the body. That's why the National Center for Complementary Alternative Medicine classifies yoga as mind-body medicine. Mind-body therapies focus on the relationships between the brain, mind, body, and behavior and their effects on health and illness. The practice of yoga also integrates the physical, mental and spiritual components of the individual to improve health and well-being. Therefore, yoga is not only a science but also an art of healthy living. It is widely used for health promotion, disease prevention, and as a possible treatment for neurological disorders. Studies investigating its effects on various neurological diseases such as multiple sclerosis, Parkinson's, dementia, epilepsy, Alzheimer's disease, headaches and stroke have reported that yoga practice is effective on disease symptoms, balance, strength, flexibility, cognitive status, depression, anxiety and quality of life. Considering the positive effects of yoga on health in neurological diseases; It can be said that it is a reasonably safe, cost-effective, feasible and promising method for patients. It is very important that nurses, as health professionals who play the most important role in the education of patients, are informed about the available complementary and integrative methods that can manage and control the symptoms in neurological diseases. In addition, nurses should show the necessary information and care to ensure that patients avoid undesirable effects, especially while performing advanced yoga practices. The aim of this review is to evaluate the use of yoga in neurological diseases and to examine its effect on health. Keywords: Nursing, neurology, yoga.
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