Yoğun bakım ünitemizdeki intoksikasyon olgularının geriye dönük incelenmesi

Totoz, Tolga; Türk, Hacer Şebnem; Sayin, Pınar; Çınar, Ayşe Surhan; Yıldırım, Çiğdem; Oba, Sibel

doi:10.5350/semb2013470204

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…It has been mentioned in similar studies that a significant portion of those attempting suicide have previously been diagnosed with a psychiatric disorder (7,9). Especially in cases of depressive disorders, a high occurrence of suicide attempts is noted, often involving medications used in their treatment.…”

Section: Discussionmentioning

confidence: 96%

Evaluation of Necessity for Intensive Care Stay, Mortality, and Morbidity in Poisoning Cases Admitted to the Emergency Department

ALTINBAŞ

2023

targetmedj

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Aim: Intoxications can occur as a result of the ingestion of the drugs or substances with a suicidal purpose or unintentional exposure to toxic substances. Patients are treated in emergency department, ward or intensive care unit. Materials and Methods:We recorded demographic data of patients, including age, gender, coexisting medical conditions, and psychiatric history. The factors causing acute intoxication, the Glasgow Coma Scale (GCS) score at the time of admission, suicidal intent, the need for hospitalization (ward or intensive care unit), and mortality status were assessed. Results: A total of 120 patients were included in the study. 67 patients (55.8%) were identified with suicidal intent. The ratio of suicidal intent among females was significantly higher compared to males (p=0.005).8% of the patients were monitored in the emergency department, 9.2% in the general ward, and 55% in the intensive care unit.Among patients with a diagnosis of suicide, no mortality was observed. It was noted that 7 patients who were deceased had methanol intoxication, and 2 had mushroom-related intoxication. Among patients diagnosed with suicide, the most common causes of intoxication were analgesics (49.25%), antidepressants (25.37%), and antipsychotics (23.88%). Conclusion:The ready availability and widespread and irregular use of antidepressants and analgesics contribute to frequent ingestion of these drugs for suicidal intent. In terms of public health, paying attention to regional mushroom consumption is crucial for reducing related fatalities.

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Section: Discussionmentioning

confidence: 96%

Evaluation of Necessity for Intensive Care Stay, Mortality, and Morbidity in Poisoning Cases Admitted to the Emergency Department

ALTINBAŞ

2023

targetmedj

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“…In different studies, intoxication mortality rates range between 0.2% and 23.5% [7] [14] [16] [24]. Kose et al showed that 29.4% of the patients needed mechanical ventilation support and the mortality rater in their findings was 23.5% [25].…”

Section: Discussionmentioning

confidence: 99%

“…Medical drugs has been reported as the most common cause of intoxication, both in studies conducted in different countries of the world and in our country. It was previously reported that the antidepressants, antibiotics, analgesics, benzodiazepines are the most frequently used drugs, in different proportions[7] [8] [9][13] [14] [15][16]…”

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confidence: 99%

A Retrospective Analysis of Intoxicated Patients Admitted to the Intensive Care Unit: A Single-Institution Assessment in the Post-Pandemic Period

Arikan,

Yeşilkaya,

Taşdelen

et al. 2024

JBM

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Background: The aim of this study was to evaluate the clinical and epidemiological characteristics of patients with acute intoxication admitted to the Intensive Care Unit (ICU). Material and Methods: An observational retrospective study was conducted on intoxicated patients who admitted to ICU between January 2022 and January 2024. Data were collected from the patients medical records. The demographic characteristics, causes of intoxications, clinical parameters, the mean stay in the ICU, treatment modalities and prognosis were recorded. Results: A total of 2875 critically ill patients were admitted during the study period, and 109 (3.79%) of them were acute intoxications. Their mean of ages was 38.09 ± 12.29. The female-to-male ratio was 1.37/1. Drugs were found to be the primary cause (62.39%) of intoxications, and analgesics, antidepressants, and antibiotics were the most frequent agents. Suicidal attempts were present in 66 patients, most of them were female (62.13%) and between 17 -24 years (40.91%). The other common causes of intoxications were carbon monoxide (CO) (22.02%), methyl/ethyl alcohol (8.26%) and mushroom (5.50%). The mean stay in the ICU was 2.69 ± 0.89 days. Mechanical ventilation was applied to 10 of our patients. Renal replacement therapy was required in 6 patients. Despite all treatments, 6 of our patients died, and we found the mortality rate to be 5.50%. Conclusion: Intoxications were more frequent in young female patients and drugs were the most common cause with suicidal intent. Unfortunately, CO poisoning continues to be a very important problem in our city. These findings provided significant information about the characteristics of intoxications in Karabuk.

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“…Bunun yanında pestisitlerden tarım ilacı, fare zehiri, koroziv maddelerden çamaşır suyu, tuz ruhu, akü suyu ve kolonya ayrıca karbonmonoksit inhalasyonu ve yılan sokması ise diğer intoksikasyon nedenleri arasındaydı. Literatürde bulunan ve ülkemizde farklı illerde yapılmış olan çalışmalarda da intihar girişimi için benzer sıklıkta ve aynı grup ilaçların kullanıldığı bildirilmiştir (9,10). İntoksikasyon tek ilaç veya kimyasal madde ile gerçekleşebileceği gibi birden fazla madde ve/veya ilaç alarak da meydana gelebilir.…”

Section: Bulgularunclassified

Retrospective Evaluation of Four-Year Acute Intoxication Cases Followed-up in Intensive Care Unit

Kosovalı¹,

Yıldız²

2019

tybd

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Objective: Acute intoxication is a life-threatining clinical issue. Therefore, patients need follow-up in the intensive care unit (ICU). In this study, we aimed to evaluate the incidence, demographic characteristics, intoxication agents and mortality rate in patients diagnosed with acute intoxication in our ICU. Materials and Methods: The records of the patients who were diagnosed with acute intoxication between April 1, 2014 and March 31, 2018 were retrospectively analyzed and were included in this study. Result: Of the 300 patients included in the study, 68.7% n=206 were female, 31.3% n=94 were male and the mean age was 28.36±12.3 years. According to age groups, most patients in 21-30 years group with 37.3% n=112 rate and the least in ≥61 years group with 3.7% n=11 rate. It was detected that 94.3% n=283 of cases took drugs and/or chemical matter for suicide attempt, 5.7% n=17 of cases influenced by exposure or accidentally. Patients accepted to ICU owing to medicine intoxication (88%), chemical matter intoxication (%6.3), mushroom intoxication (4%), drug abuse (1.4%) and snakebite (0.3%). According to medicine groups; patients took most ÖZ Amaç: Akut intoksikasyon olguları hayati risk taşıyan olgulardır. Bu sebeple hastaların yoğun bakım ünitelerinde (YBÜ) takibi uygundur. Bu çalışmadaki amacımız YBÜ'ye akut intoksikasyon tanısı ile kabul edilen olguların sıklığını, demografik özelliklerini, intoksikasyon etkenlerini ve mortalite oranlarını değerlendirmektir. Gereç ve Yöntem: 1 Nisan 2014-31 Mart 2018 tarihleri arasında YBÜ'ye akut intoksikasyon tanısı ile yatırılan hastaların kayıtları retrospektif olarak incelenerek çalışmaya dahil edildi. Bulgular: Çalışmaya alınan 300 hastanın %68,7'si n=206 kadın, %31,3'ü n=94 erkek ve yaş ortalaması 28,36±12,3 idi. Yaşların gruplara göre dağılımı %37,3 n=112 oranıyla en sık 21-30 yaş arasında, %3,7 n=11 oranıyla en az 61 yaş ve üzerindeki yaş grubunda izlendi. Hastaların %94,3'ünün n=283 intihar amaçlı ilaç ve/veya kimyasal madde aldıkları, %5,7'sinin n=17 ise yanlışlıkla veya kaza sonucu maruziyetlerinin olduğu saptandı. Hastaların %88'i ilaç intoksikasyonu, %6,3'ü kimyasal madde, %4'ü mantar intoksikasyonu, %1,4'ü uyuşturucu madde alımı, %0,3'ü yılan sokması gibi nedenlerden dolayı akut intoksikasyon tanısı ile YBÜ'ye kabul edildi. Hastaların sırayla n=55 antidepresan grubu, non-steorid anti-enflamatuvar ilaç grubu n=38, analjezik grubu n=37, antigribal ilaçlar n=34 aldığı belirlendi ve en sık yaz mevsiminde (%29,7) intoksikasyon girişimi olduğu saptandı. Antidepresan grupta en sık trisiklik antidepresan ilaçlar, analjezik grubunda en sık parasetamol, antiepileptik grubunda en çok karbamazepin, antigribal ilaçlardan ibuprufen + klorfeniramin kombinasyonu, antipsikotiklerden ketiapin, anksiyolitiklerden alprazolam, OAD grubunda metformin, PPI alan hastalardan pantoprazol en sık intoksikasyon etkeni olan ajanlardır. Olguların YBÜ'de ortalama yatış süresi 1,39±1,57 gün, mortalite oranı ise %0,67 idi. Sonuç: Akut intoksikasyon olguları hayati risk taşıyan klinik tablo oluşt...

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Yoğun bakım ünitemizdeki intoksikasyon olgularının geriye dönük incelenmesi

Cited by 5 publications

References 8 publications

Evaluation of Necessity for Intensive Care Stay, Mortality, and Morbidity in Poisoning Cases Admitted to the Emergency Department

Evaluation of Necessity for Intensive Care Stay, Mortality, and Morbidity in Poisoning Cases Admitted to the Emergency Department

A Retrospective Analysis of Intoxicated Patients Admitted to the Intensive Care Unit: A Single-Institution Assessment in the Post-Pandemic Period

Retrospective Evaluation of Four-Year Acute Intoxication Cases Followed-up in Intensive Care Unit

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