Yolk sac size &amp; shape as predictors of first trimester pregnancy outcome: A prospective observational study

Suguna, B V; Sukanya, K.

doi:10.1016/j.jogoh.2018.10.016

Cited by 19 publications

(12 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most existing studies investigate the individual components of the first-trimester ultrasound for predicting miscarriage [9,25,26]. Abnormal yolk sac size and appearance have been reported to be useful markers for miscarriage prediction before the demonstration of fetal viability [27]. However, in presence of an established viable intrauterine pregnancy, its usefulness is limited.…”

Section: Discussionmentioning

confidence: 99%

Automated prediction of early spontaneous miscarriage based on the analyzing ultrasonographic gestational sac imaging by the convolutional neural network: a case-control and cohort study

Wang

Zhang

Yin

et al. 2022

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

Background It is challenging to predict the outcome of the pregnancy when fetal heart activity is detected in early pregnancy. However, an accurate prediction is of importance for obstetricians as it helps to provide appropriate consultancy and determine the frequency of ultrasound examinations. The purpose of this study was to investigate the role of the convolutional neural network (CNN) in the prediction of spontaneous miscarriage risk through the analysis of early ultrasound gestational sac images. Methods A total of 2196 ultrasound images from 1098 women with early singleton pregnancies of gestational age between 6 and 8 weeks were used for training a CNN for the prediction of the miscarriage in the retrospective study. The patients who had positive fetal cardiac activity on their first ultrasound but then experienced a miscarriage were enrolled. The control group was randomly selected in the same database from the fetuses confirmed to be normal during follow-up. Diagnostic performance of the algorithm was validated and tested in two separate test sets of 136 patients with 272 images, respectively. Performance in prediction of the miscarriage was compared between the CNN and the manual measurement of ultrasound characteristics in the prospective study. Results The accuracy of the predictive model was 80.32% and 78.1% in the retrospective and prospective study, respectively. The area under the receiver operating characteristic curve (AUC) for classification was 0.857 (95% confidence interval [CI], 0.793–0.922) in the retrospective study and 0.885 (95%CI, 0.846–0.925) in the prospective study, respectively. Correspondingly, the predictive power of the CNN was higher compared with manual ultrasound characteristics, for which the AUCs of the crown-rump length combined with fetal heart rate was 0.687 (95%CI, 0.587–0.775). Conclusions The CNN model showed high accuracy for predicting miscarriage through the analysis of early pregnancy ultrasound images and achieved better performance than that of manual measurement.

show abstract

Section: Discussionmentioning

confidence: 99%

Automated prediction of early spontaneous miscarriage based on the analyzing ultrasonographic gestational sac imaging by the convolutional neural network: a case-control and cohort study

Wang

Zhang

Yin

et al. 2022

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

show abstract

“…Es gibt aber zahlreiche Berichte von normalen Schwangerschaftsverläufen und gesun- den Neugeborenen, bei denen in der Frühschwangerschaft ein auffällig großer Dottersack beobachtet wurde. In manchen Studien war es nicht der auffällige Durchmesser des Dottersacks, sondern sein Aussehen, das sich als prognostisch für ein Abortgeschehen erwies [7]. Aus Hier steht eine Anzeige.…”

Section: Dottersack Als Prognosefaktorunclassified

Der Dottersack – ein wichtiger Marker beim Ultraschall in der Frühschwangerschaft

Brezinka

2019

J. Gynäkol. Endokrinol. AT

View full text Add to dashboard Cite

ist ein wenig beachteter Nebenbefund beim Ultraschall in der Frühschwangerschaft. Dieser wichtige Begleiter des winzigen Kindes übernimmt eine Zeitlang seine Blutproduktion, bevor er dann ab der 10. SSW langsam obliteriert. Im Ultraschall ist der Dottersack ein wichtiges Orientierungsmerkmal und eine diagnostische Hilfe. Das allererste Zeichen einer intrauterinen Schwangerschaft, das wir im Ultraschall erkennen, ist die meist kreisrunde, echoarme Struktur, die im Ultraschalljargon "Fruchtsack" genannt wird. Der Fruchtsack entsteht zwar durch den Embryo, er ist genau genommen ein vom mütterlichen Endometrium gebildetes "Drumherum", in dem sich die Schwan

show abstract

“…So, the yolk sac is important, and then the embryo appears and the heart starts beating (5) . The presence of a yolk sac is definitive evidence of a genuine gestational sac (6) .…”

Section: Introductionmentioning

confidence: 99%

“…Approximately 30-40% of all implantations are lost to spontaneous abortion, and the vast majority of these abortions occur within the first trimester (6) . If fetal cardiac activity has been established, however, the chance of a spontaneous abortion is reduced to 2-5% (7) .…”

Section: Introductionmentioning

confidence: 99%

Is Sonographic Morphology of Early Embryonic Complex Can Predict of Pregnancy Outcome?

Seliha¹,

Eltoutongy²,

Bediary³

et al. 2022

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

Background: There is a high rate of spontaneous abortion in the first trimester of pregnancy, affecting an estimated 30-40% of all implantations. A low implantation location, a large or irregular yolk sac, a weak decidual reaction, and a sluggish embryonic heart rate are just few of the many sonographic indicators of predictors of poor result that have been identified by many authors. The aim of the current study is to investigate the predictive value of abnormal gestational sac morphology at 6-8 week for the pregnancy outcome. Patients and methods:The present study was a follow up observational study that included 188 patients aged 18-35 years, who presented at 6-8 weeks of gestation between May 2019 and February 2021 at Mansoura University Hospital's Antenatal Care Outpatient Clinic. Results: Larger gestational sac was associated with abnormal pregnancy outcome, like abortion (2.25±0.58 cm), preterm labor (2.33±0.0 cm), intrauterine feal death (IUFD) (2.70±0.28 cm), intrauterine growth retardation (IUGR) (2.93±0.93 cm) and abruptio placenta (3.45±2.19 cm). Also, larger yolk sac was also associated with abnormal pregnancy outcome, like preterm labor (5.0±0.0 cm), IUGR (5.57±1.07 cm), and IUFD (5.50±0.71 cm). Moreover, higher fetal HR was associated with abnormal pregnancy outcome, like preterm labor (155.0±0.0 bpm), IUFD (157.50±3.53 bpm), and IUGR (171.0±4.58 bpm). Conclusion: Statistically highly significant correlations were found between both yolk sac size and fetal heart rate, and abnormal pregnancy outcome, despite the fact that there was no link between gestational sac size and an increased risk of a negative pregnancy outcome.

show abstract

Yolk sac size & shape as predictors of first trimester pregnancy outcome: A prospective observational study

Cited by 19 publications

References 16 publications

Automated prediction of early spontaneous miscarriage based on the analyzing ultrasonographic gestational sac imaging by the convolutional neural network: a case-control and cohort study

Automated prediction of early spontaneous miscarriage based on the analyzing ultrasonographic gestational sac imaging by the convolutional neural network: a case-control and cohort study

Der Dottersack – ein wichtiger Marker beim Ultraschall in der Frühschwangerschaft

Is Sonographic Morphology of Early Embryonic Complex Can Predict of Pregnancy Outcome?

Contact Info

Product

Resources

About