This research digs into the convoluted topography of water contamination in Zambia's Copperbelt Province, with an emphasis on the important contributions of mining and sewage effluent. This report provides major conclusions about the origins, types, and effects of contaminants in the region's water bodies based on a thorough review of current research and empirical evidence. Mining activities emerge as a major source of water pollution, with effluent contaminated with heavy metals, sulphates, and other compounds that pose serious hazards to aquatic ecosystems and public health. Despite efforts to improve wastewater treatment, shortcomings persist, resulting in the leakage of toxic effluent into neighboring waterways. Similarly, sewage wastewater contributes to contamination by including faecal coliforms, nutrients, oils, and heavy metals. The effects of water contamination are far-reaching, as indicated by increasing pollutant concentrations in stream sediments and downstream bodies. Aquatic life suffers from habitat destruction, diminished biodiversity, and negative health effects, while communities relying on these water supplies face increased health risks. Given these issues, the paper analyses potential solutions and recommendations for effective wastewater management, with a focus on interdisciplinary collaboration, technical innovation, and regulatory enforcement. Initiatives fostering recycling, resource recovery, and the implementation of advanced treatment technology hold promise for minimizing water pollution and maintaining sustainable water management practices in the Copperbelt Province.