Zastosowanie komórek macierzystych tkanki tłuszczowej w medycynie – najnowsze trendy

Brzezicka, Agnieszka; Kondej, Karolina; Błażyńska‐Spychalska, Agata; Spychalski, Piotr; Jankau, Jerzy; Pikuła, Michał

doi:10.15374/chpio2018016

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, the short observation time results in uncertainty regarding long-term therapeutic effects. There is a need for randomisation, meta-analyses and prospective studies to help optimize aesthetically and functionally satisfactory intervention techniques [34,45,[63][64][65].…”

Section: Treatmentmentioning

confidence: 99%

Disturbances of the stomatognathic system and possibilities of its correction in patients with craniofacial morphea

Wróblewska,

Polańska,

Mojs

et al. 2023

pdia

View full text Add to dashboard Cite

Morphea en coup de sabre and progressive hemifacial atrophy are extremely rare connective tissue disorders causing facial deformity. In extreme cases, morphological disorders are accompanied by symptoms of a clear impairment of the stomatognathic system. The aetiology of the above-mentioned diseases is still unknown. Properly planned therapy in the field of maxillofacial orthopaedics makes it possible to correct the asymmetric pattern of hard tissue growth and thus enable rehabilitation. The task of augmentation techniques is the volumetric supplementation of tissue defects resulting from atrophic processes. The degree of destruction and the extent of changes determine the method of correction. Mild and moderate defects are treated mainly with biomaterials and autologous adipose tissue. The severe course of hemifacial atrophy and morphea en coup de sabre and the associated significant tissue atrophy necessitate the search for more complex methods of treatment. In this paper, we summarize the disturbances of the stomatognathic system in patients with craniofacial morphea, together with an analysis of current treatment options.

show abstract

Section: Treatmentmentioning

confidence: 99%

Disturbances of the stomatognathic system and possibilities of its correction in patients with craniofacial morphea

Wróblewska,

Polańska,

Mojs

et al. 2023

pdia

View full text Add to dashboard Cite

show abstract

Adipose‐derived stromal cells for nonhealing wounds: Emerging opportunities and challenges

Deptuła

Brzezicka

Skoniecka

et al. 2021

Medicinal Research Reviews

Self Cite

View full text Add to dashboard Cite

Wound healing complications affect thousands of people each year, thus constituting a profound economic and medical burden. Chronic wounds are a highly complex problem that usually affects elderly patients as well as patients with comorbidities such as diabetes, cancer (surgery, radiotherapy/chemotherapy) or autoimmune diseases. Currently available methods of their treatment are not fully effective, so new solutions are constantly being sought. Cell‐based therapies seem to have great potential for use in stimulating wound healing. In recent years, much effort has been focused on characterizing of adipose‐derived mesenchymal stromal cells (AD‐MSCs) and evaluating their clinical use in regenerative medicine and other medical fields. These cells are easily obtained in large amounts from adipose tissue and show a high proregenerative potential, mainly through paracrine activities. In this review, the process of healing acute and nonhealing (chronic) wounds is detailed, with a special attention paid to the wounds of patients with diabetes and cancer. In addition, the methods and technical aspects of AD‐MSCs isolation, culture and transplantation in chronic wounds are described, and the characteristics, genetic stability and role of AD‐MSCs in wound healing are also summarized. The biological properties of AD‐MSCs isolated from subcutaneous and visceral adipose tissue are compared. Additionally, methods to increase their therapeutic potential as well as factors that may affect their biological functions are summarized. Finally, their therapeutic potential in the treatment of diabetic and oncological wounds is also discussed.

show abstract

Zastosowanie komórek macierzystych tkanki tłuszczowej w medycynie – najnowsze trendy

Cited by 2 publications

References 0 publications

Disturbances of the stomatognathic system and possibilities of its correction in patients with craniofacial morphea

Disturbances of the stomatognathic system and possibilities of its correction in patients with craniofacial morphea

Adipose‐derived stromal cells for nonhealing wounds: Emerging opportunities and challenges

Contact Info

Product

Resources

About