Zero dimensional Graphene Quantum Dots self-assembled collagen 3D bio-matrices for soft tissue regeneration

Ahina, Kannoth Madappurakkal; Kannan, Kiruba; Vijayan, Vinu; Sreekumar, Sreelekshmi; Lakra, Rachita; Kiran, Manikantan Syamala

doi:10.1016/j.mtcomm.2023.107244

Materials Today Communications

2023

DOI: 10.1016/j.mtcomm.2023.107244

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Zero dimensional Graphene Quantum Dots self-assembled collagen 3D bio-matrices for soft tissue regeneration

Kannoth Madappurakkal Ahina,

Kiruba Kannan,

Vinu Vijayan

et al.

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2024

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Cited by 3 publications

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The role of graphene quantum dots in cutting‐edge medical therapies

Arab,

Jafari,

Shahi

2024

Polymers for Advanced Techs

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Graphene quantum dots (GQDs), owing to their unique optical, electrical, and chemical properties, have emerged as promising nanomaterials for various biomedical applications. This review provides a comprehensive overview of the latest advancements in the utilization of GQDs in tissue engineering, wound healing, drug delivery systems, and other biomedical therapies. The inherent properties of GQDs, including high biocompatibility, tunable photoluminescence, and significant surface area, make them ideal candidates for enhancing medical treatments and diagnostics. In tissue engineering, GQDs improve the mechanical and biological performance of scaffolds, promoting cell proliferation and differentiation. For wound healing, GQDs enhance antimicrobial activity and facilitate faster tissue regeneration. Their potential in DDS is highlighted by their ability to deliver therapeutic agents efficiently, ensuring targeted and controlled release. Additionally, GQDs play a crucial role in biomedical therapies, particularly in cancer treatment, by enhancing drug efficacy and reducing side effects. While GQDs offer significant potential in enhancing medical treatments and diagnostics, challenges such as understanding their long‐term biocompatibility, potential cytotoxicity at higher concentrations, and the need for standardized synthesis methods remain critical areas for further research. This review also discusses the future directions and opportunities for GQDs, emphasizing their transformative potential in advancing modern healthcare solutions. The insights presented here contribute to the expanding field of GQD research, highlighting their potential to significantly enhance patient outcomes and drive healthcare innovations.

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The role of graphene quantum dots in cutting‐edge medical therapies

Arab,

Jafari,

Shahi

2024

Polymers for Advanced Techs

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Nanocomposites of Three-Dimensional Graphene Nanofoams with Polymers—Fundamentals and Progressions

Kausar

2024

Polymer-Plastics Technology and Materials

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Graphene-Oxide Peptide-Containing Materials for Biomedical Applications

Gostaviceanu,

Gavrilaş,

Copolovici

et al. 2024

IJMS

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This review explores the application of graphene-based materials (GBMs) in biomedicine, focusing on graphene oxide (GO) and its interactions with peptides and proteins. GO, a versatile nanomaterial with oxygen-containing functional groups, holds significant potential for biomedical applications but faces challenges related to toxicity and environmental impact. Peptides and proteins can be functionalized on GO surfaces through various methods, including non-covalent interactions such as π–π stacking, electrostatic forces, hydrophobic interactions, hydrogen bonding, and van der Waals forces, as well as covalent bonding through reactions involving amide bond formation, esterification, thiol chemistry, and click chemistry. These approaches enhance GO’s functionality in several key areas: biosensing for sensitive biomarker detection, theranostic imaging that integrates diagnostics and therapy for real-time treatment monitoring, and targeted cancer therapy where GO can deliver drugs directly to tumor sites while being tracked by imaging techniques like MRI and photoacoustic imaging. Additionally, GO-based scaffolds are advancing tissue engineering and aiding tissues’ bone, muscle, and nerve tissue regeneration, while their antimicrobial properties are improving infection-resistant medical devices. Despite its potential, addressing challenges related to stability and scalability is essential to fully harness the benefits of GBMs in healthcare.

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Zero dimensional Graphene Quantum Dots self-assembled collagen 3D bio-matrices for soft tissue regeneration

Cited by 3 publications

References 44 publications

The role of graphene quantum dots in cutting‐edge medical therapies

The role of graphene quantum dots in cutting‐edge medical therapies

Nanocomposites of Three-Dimensional Graphene Nanofoams with Polymers—Fundamentals and Progressions

Graphene-Oxide Peptide-Containing Materials for Biomedical Applications

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