Zero Operative Mortality for Gastric Cancer with Hepatic Cirrhosis.

Takeda, Jinryo; Hashimoto, Ken; Tanaka, Takaho; Koufuji, Kikuo; Yamana, Hideaki; Kakegawa, Teruo

doi:10.2739/kurumemedj.38.117

Cited by 10 publications

(11 citation statements)

References 8 publications

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“…In the present series, the estimated 5-year survival rate following a curative resection was 54% overall; being 66% for those with Child's class A and 11% for those with Child's class B or C. As expected, this survival rate is worse than that observed for patients without LC [12]. However, our longterm outcomes are comparable to those in other studies of patients with gastric cancer combined with LC [8,13]. While the causes of death for patients with Child's class A were most commonly related to the recurrence of gastric cancer, the most common causes for patients with Child's class B or C were cirrhosis related, such as hepatic failure or hepatoma, followed by the postoperative complications.…”

Section: Discussionsupporting

confidence: 64%

Clinical Outcomes of Patients with Liver Cirrhosis Who Underwent Curative Surgery for Gastric Cancer: A Retrospective Multi-center Study

et al. 2007

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We investigated early postoperative morbidity, mortality, and long-term outcomes in patients with liver cirrhosis (LC) who had undergone curative surgery for gastric cancer. The medical records of patients with LC who had undergone radical gastrectomy for gastric adenocarcinoma between January 1996 and September 2006 were retrospectively reviewed. A total of 57 patients were enrolled in this study. Forty-six patients (81%) were classified into Child's class A. In 22 patients (39%) postoperative complications developed, the most common being ascites (23%), followed by wound infection and hepatic encephalopathy. Postoperative ascites occurred more frequently in patients with Child's class B or C than in those with class A (63.6% vs 13%, P = 0.001). Massive ascites developed in 4 patients, 3 of whom had Child's class B and underwent D2 lymph node (LN) dissection, and 1 of whom had Child's class C and a D1 LN dissection. Postoperative mortality occurred in 5 patients (9%), with a significantly higher mortality rate for patients with Child's class B or C than for those with class A (27.2% vs 4.3%, P = 0.045). With a median follow-up of 32 months, the estimated 5-year survival rate for all patients was 54%. Regardless of the tumor depth, overall survival was longer for patients with Child's class A than for those with Child's class B or C. These results demonstrated that radical gastrectomy with extended LN dissection is feasible in patients with compensated LC. For patients with moderate to severe hepatic dysfunction, however, D1 or less extensive LN dissection may be the more reasonable surgical procedure.

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Section: Discussionsupporting

confidence: 64%

Clinical Outcomes of Patients with Liver Cirrhosis Who Underwent Curative Surgery for Gastric Cancer: A Retrospective Multi-center Study

et al. 2007

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“…Therefore, it is difficult to determine whether cirrhotic patients are suitable for gastric cancer treatment, for which the prognosis is comparatively good. Several studies have focused on the clinical outcomes of radical gastrectomy for patients with gastric cancer and comorbid LC [21][22][23][24][25][26]. These studies indicate that 10-20 % of LC patients develop post-operative intractable ascites, and perioperative mortality is approximately 10 %.…”

Section: Discussionmentioning

confidence: 98%

Outcomes of ESD for patients with early gastric cancer and comorbid liver cirrhosis: a propensity score analysis

et al. 2014

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“…On the other hand, the most frequent causes of death for cirrhotic patients after gastrectomy for gastric cancer were cirrhosis-related death, such as gastrointestinal bleeding or hepatic failure or hepatoma. 29,30 There are two possible explanations for why few patients die of liver-associated disease after esophagectomy. First, esophagogastrectomy involves a complete devascularization of the esophagogastric varices, which causes less gastrointestinal bleeding.…”

Section: Figmentioning

confidence: 98%

Esophageal Cancer With Cirrhosis of the Liver: Results of Esophagectomy in 18 Consecutive Patients

et al. 2000

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Zero Operative Mortality for Gastric Cancer with Hepatic Cirrhosis.

Cited by 10 publications

References 8 publications

Clinical Outcomes of Patients with Liver Cirrhosis Who Underwent Curative Surgery for Gastric Cancer: A Retrospective Multi-center Study

Clinical Outcomes of Patients with Liver Cirrhosis Who Underwent Curative Surgery for Gastric Cancer: A Retrospective Multi-center Study

Outcomes of ESD for patients with early gastric cancer and comorbid liver cirrhosis: a propensity score analysis

Esophageal Cancer With Cirrhosis of the Liver: Results of Esophagectomy in 18 Consecutive Patients

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