Mrs. SM, 49 years old, is a teacher. She was pregnancy when she was 23 years old, but met an inevitable abortion in 40 days. She has never been conceived again since then. After she is 40 years old, she starts to worry on her reproductive function and seeks diagnosis and treatment. She is found blockages on both of her fallopian tubes and failed two times of IVF. She visits me when she is 49 years old who has missed two months of her menstruation. Due amenorrhea's occurrence, Gynaecologists refuse another IVF to her. She also manifested exhaustion, hot flashes, depression, tinnitus, insomnia and other symptoms with red tongue and wiry-fine pulse.