2019
DOI: 10.1016/j.gastre.2018.10.002
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Zieve's syndrome, an underdiagnosed entity

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“…Even if the patient truly had a significant alcohol exposure prior to transplant, the patient's RBC localized PEth was likely diminished as he had substantial operative blood loss and transfusions. Likewise, in individuals with severe acute alcohol hepatitis and concurrent Zieve's syndrome (Abughanimeh et al, 2019;Choudhry et al, 2019;Gotor Delso et al, 2019;Senatore & McDonald, 2016), RBC destruction may be responsible for negative PEth testing despite recent alcohol intake and we suspect this occurred in one of our patients. As EtG and EtS have been detected in hair samples, these hair biomarkers may be most appropriate in such scenarios (Cappelle et al, 2018;Crunelle et al, 2014;Sterneck et al, 2014).…”
Section: Discussionmentioning
confidence: 69%
“…Even if the patient truly had a significant alcohol exposure prior to transplant, the patient's RBC localized PEth was likely diminished as he had substantial operative blood loss and transfusions. Likewise, in individuals with severe acute alcohol hepatitis and concurrent Zieve's syndrome (Abughanimeh et al, 2019;Choudhry et al, 2019;Gotor Delso et al, 2019;Senatore & McDonald, 2016), RBC destruction may be responsible for negative PEth testing despite recent alcohol intake and we suspect this occurred in one of our patients. As EtG and EtS have been detected in hair samples, these hair biomarkers may be most appropriate in such scenarios (Cappelle et al, 2018;Crunelle et al, 2014;Sterneck et al, 2014).…”
Section: Discussionmentioning
confidence: 69%