Zika virus: A pandemic in progress

Abstract

The world is facing a number of emerging infections. The latest outbreak of Zika virus infection has only added to the suffering. The WHO declared a state of emergency in the affected countries and has issued alarms worldwide. The paucity of literature leading to lack of clear guidelines is one of the most important factors resulting in a higher number of cases. The absence of clinical vaccine and an antiviral drug may prove to be a really grave situation. The present paper throws some light on this new emerging virus that has been known to man since 1947.

Bedaquiline has potential for targeting tuberculosis reservoirs in the central nervous system

“…1 In the most recent TB drug pipeline, there are several novel agents, many of which are currently undergoing clinical trials to determine their potential against TB. [2][3][4][5][6][7][8] Amongst them, BDQ has proven to be a promising rst-in-class US FDA approved anti-TB agent, which belongs to the diarylquinoline class of antibiotics. BDQ is proposed for the treatment of multidrugresistant tuberculosis (MDR-TB) in combination with other active anti-TB drugs, when an effective therapy regimen could not be established.…”

Skin manifestations are common and associated with a higher prevalence of congenital abnormalities in Zika virus infection

“…Potential ascertainment bias may have occurred because only published cases were included in this review. However, considering that previous reports suggest that only 20% of individuals experience symptoms during Zika virus infection (maculopapular rash, arthralgia, malaise, headache, fever, conjunctivitis), the report by Andersen et al . of 91.3% in 264 patients and this report of 83% in 841 patients suggest that skin involvement might be more common in Zika patients presenting for healthcare than previously reported.…”

Age related hearing loss- A review

“…The treatment options for ARHL are the use of hearing aids. However, fewer older adults are using hearing aids.And thus therole of dissemination of healthcare information to the geriatric population is very important, especially in resource limited settings and the agencies working in this field for the spread of healthcare information should work really hard [71][72][73][74][75][76][77][78][79][80][81][82][83]. The enhanced screening and intervention programs to identify older adults who would benefit from amplification are needed to improve hearing in the elderly population.…”