Zika Virus Infection, Cambodia, 2010

Heang, Vireak; Yasuda, Chadwick Y.; Sovann, Ly; Haddow, Andrew D.; Rosa, Amelia P. Travassos da; Tesh, Robert B.; Kasper, Matthew R.

doi:10.3201/eid1802.111224

Cited by 250 publications

(211 citation statements)

References 10 publications

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“…About 20-25% of people infected with ZIKV develop symptoms which usually include rash, fever, arthralgia and conjunctivitis as the most common symptoms and headache, vomiting and oedema in a minority [29]. Moreover, ZIKV infection has been suggested to be associated with more severe neurological complications including microcephaly, a serious birth defect characterized by babies with small heads and incomplete brain development born from infected mothers.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Zika virus: a new pandemic threat

Al‐Qahtani

Nazir

Al-Anazi

et al. 2016

J Infect Dev Ctries

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Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family and is related to dengue, Chikungunya, West Nile, yellow fever, and Japanese encephalitis viruses. ZIKV was first discovered in Uganda in 1947. Different species of mosquito from the Aedes genus, mainly A. aegypti and A. albopictus are the vectors responsible for ZIKV infection in humans. It is also reported that ZIKV is transmitted congenitally, sexually, and through blood donation. Until recently, ZIKV outbreaks were sporadic and self-limiting. The first large epidemic was reported from Yap Island in 2007 followed by an outbreak of Zika fever in French Polynesia in 2013. Brazil is the epicenter of the current ZIKV epidemic which is rapidly spreading across the Americas. ZIKV infection remained relatively less studied in view of its low case numbers, and low clinical impact relative to other arboviruses. However, all this is set to change with its rapid spread in the Western hemisphere and suspected complications particularly microcephaly in newborn babies with ZIKV infected mothers. ZIKV is expected to substantially add to both shortterm and long-term economic burden of the effected countries. Due to the large number of people travelling across the borders and some reported cases of transmission of ZIKV via contaminated blood, screening and identification of asymptomatic infected individuals are important.

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Section: Clinical Manifestationsmentioning

confidence: 99%

Zika virus: a new pandemic threat

Al‐Qahtani

Nazir

Al-Anazi

et al. 2016

J Infect Dev Ctries

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“…The disease is acute but self-limiting. Symptoms across six case clusters from 1962-2010 are reviewed by Heang et al (2012). The observation of Guillain-Barré syndrome among Zika cases in Polynesia represented an increase in the potential clinical severity of the disease (Roth et al, 2014).…”

Section: Clinical Presentation Of American Zika Virusmentioning

confidence: 99%

Zika virus: a previously slow pandemic spreads rapidly through the Americas

Gatherer

Kohl

2016

Journal of General Virology

271

208

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“…Commonly reported symptoms include malaise, headache, maculopapular rash, myalgia, arthralgia, conjunctivitis, and fever. 1,3 Diagnosis can be confirmed by demonstration of specific antibodies against Zika virus in serum or by PCR detection of the virus. [4][5][6] Detailed serologic testing of the Yap Islands Zika virus outbreak in 2007 showed limited cross-reactivity with IgM against other flaviviruses, including dengue virus.…”

mentioning

confidence: 99%

Zika Virus Infection Acquired During Brief Travel to Indonesia

Kwong¹,

Druce²,

Leder³

2013

The American Society of Tropical Medicine and Hygiene

163

109

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Abstract. Zika virus infection closely resembles dengue fever. It is possible that many cases are misdiagnosed or missed. We report a case of Zika virus infection in an Australian traveler who returned from Indonesia with fever and rash. Further case identification is required to determine the evolving epidemiology of this disease.A previously healthy 52-year-old Australian woman had malaise and rash after a 9-day holiday to Jakarta, Indonesia. On arrival in Australia, she initially reported some fatigue and non-specific malaise, followed by a prominent headache. The headache subsequently began to subside, but on day 4 of her symptoms, a maculopapular rash developed that started on her trunk before spreading to her back and limbs, but not her face. This rash was accompanied by generalized myalgia, some loose bowel movements, and an occasional dry cough. She did not experience any significant sweats or rigors.Examination on day 5 of her illness showed mild bilateral conjunctivitis and a diffuse maculopapular rash, but no evidence of lymphadenopathy or tenosynovitis. Investigations at this time showed a total leukocyte count of 3.6

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Zika Virus Infection, Cambodia, 2010

Cited by 250 publications

References 10 publications

Zika virus: a new pandemic threat

Zika virus: a new pandemic threat

Zika virus: a previously slow pandemic spreads rapidly through the Americas

Zika Virus Infection Acquired During Brief Travel to Indonesia

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