Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?

Melo, A. S. Oliveira; Malinger, G.; Ximenes, R.; Szejnfeld, Patricia Oliveira; Sampaio, Simone Alves; Filippis, Ana María Bispo de

doi:10.1002/uog.15831

Cited by 1,096 publications

(729 citation statements)

References 7 publications

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“…Markedly, certain other characteristic features, for example chorioretinitis and hepatosplenomegaly, have not been reported [74]. Ultrasonographic examination shows intracranial calcifications specifically over the white matter of the frontal lobes, lentostriatal vessels, caudate, cerebellum, around the lateral and fourth ventricles, cerebral atrophy, dysgenesis of corpus callosum, enlarged cisterna magna, vermis and thalami, asymmetrical cerebral hemispheres, midline shift, severe unilateral ventriculomegaly and thinning of the parenchyma on the dilated side, brainstem and pons [68,74].…”

Section: Intrauterine (Congenital) Infectionmentioning

confidence: 99%

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Zika virus disease: a current review of the literature

et al. 2016

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Section: Intrauterine (Congenital) Infectionmentioning

confidence: 99%

“…The clinical characteristics of ZIKV disease in pregnant women are similar to those of non-pregnant women. Currently, no evidence indicates that pregnancy confers increased susceptibility to ZIKV infection or severe clinical symptoms [52,68].…”

Section: Adultsmentioning

confidence: 99%

Zika virus disease: a current review of the literature

et al. 2016

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“…Besides, substantial evidence also indicates the transmission of ZIKV from the mother to the fetus during pregnancy. [2] Moreover, sexual transmission of ZIKV to partners of affected male travelers returning from the high-risk region has also been reported. [3] Zika has a similar clinical presentation and transmission cycle as other mosquito-borne diseases.…”

Section: Introductionmentioning

confidence: 99%

A Cross-sectional Survey on the Knowledge and Attitudes towards Zika Virus and its Prevention among Residents of Selangor, Malaysia

Arief¹,

Hassali²,

Saleem³

et al. 2017

JPPCM

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Objective: The objectives of this study were to evaluate the knowledge and attitudes towards ZIKV and its prevention among residents of Selangor, Malaysia. Methods: A pre-tested, selfadministered, cross-sectional survey involving 400 participants was conducted from January to February 2016 in Selangor, a most populated state of Malaysia. Participants were selected using a purposive sampling approach. Descriptive and inferential statistical tests were applied to analyze the data. Results: Of 400 surveys included in the final analysis, 286 (71.5%) respondents showed good knowledge towards ZIKV. The mean knowledge score of the participants was 10.94 ± 3.89. A total of 298 (74.5%) respondents showed a positive attitude towards ZIKV and its prevention. The mean attitude score of the participants was 7.10 ± 2.80 (based on 10 questions). One-third of participants (n=132, 33%) did not consider the need of any protective measure if the male partner is suspected of having ZIKV. A large proportion of respondents (n=190, 47.5%) did not consider Malaysia at risk of ZIKV. Participants' main source of information about ZIKV was the internet. Conclusion: The findings of this study highlighted important gaps in the knowledge and attitudes of Selangor residents towards ZIKV and its prevention. There is a need for developing customized interventions to bridge these gaps as it is critical to prevent the spread of ZIKV in Malaysia.

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“…During Tahiti outbreak in 2013 it was reported that it can transmitted through sexual contact from an infected individuals [1,14]. Most recent report confirmed the vertical transmission of ZIKV from mother to fetus [26]. …”

Section: Introductionmentioning

confidence: 99%

Emerging Zika virus disease: a public health emergency of global concern

2016

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Infectious diseases remain a leading source of human morbidity and mortality. Recently, emerging infectious diseases are dominated by zoonoses, and eventually rising considerably. Their emergence is dependent on various factors especially, socioeconomic, environmental and ecological factors etc. Recently, the swift spread of Zika virus (ZIKV) through the Americas, simultaneously with the association of infection with microcephaly and Guillain-Barré syndrome, has strained this previously overlooked virus into the global attention. ZIKV is an emerging mosquito-borne Flavivirus, identified in rhesus monkey in 1947 in Uganda, and eventually in human in 1952. Considering the severity and recent spread over Americas, it has been declared as a public health emergency of international concern, and expected number of cases may be around three to four million. Therefore, it's important for all to assess the risk and be prepared in all possible ways before it makes a huge loss and spread globally. This news tries to discuss the possible reasons for its spread, risk assessment, and options to obliterate ZIKV.

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Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?

Cited by 1,096 publications

References 7 publications

Zika virus disease: a current review of the literature

Zika virus disease: a current review of the literature

A Cross-sectional Survey on the Knowledge and Attitudes towards Zika Virus and its Prevention among Residents of Selangor, Malaysia

Emerging Zika virus disease: a public health emergency of global concern

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