Zika Virus: the Latest Newcomer

Saiz, Juan-Carlos; Vázquez-Calvo, Ángela; Blázquez, Ana B.; Merino-Ramos, Teresa; Escribano-Romero, Estela; Martín-Acebes, Miguel A.

doi:10.3389/fmicb.2016.00496

Cited by 171 publications

(203 citation statements)

References 163 publications

(264 reference statements)

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“…In one volunteer, a febrile illness of 4 days' duration developed 82 hours after subcutaneous inoculation of Zik a virus [12].…”

Section: Introductionmentioning

confidence: 99%

Zika Virus Infection.

Albeshry.¹,

Alastal.²,

Bahamdain.³

et al. 2017

IJAR

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Aim:To assess Public knowledge, attitudes and behavior towards Zika virus in Saudi Arabia. Methods: A prospective cross-sectional survey conducted for a period of 2 months from June-2016 to July-2016. Knowledge scoring was given basedon the percentage of correct responses. Data were collected using a self-prepared questionnaire and analyzed using descriptive statistics. Associationof respondent's knowledge score with sex, age group, and educational level, was analyzed by Chi-square test. Results:The total sample size of the present study was 284 members, of which 187 were males and 97 were females. There was no statistical difference regarding Zika virus infection in the knowledge between both genders. There was no statistical difference regarding Zika virus infection in the knowledge between age groups. The majority of respondents were found by completing secondary schooling with 66 (36.7%), followed by no education with 50 (27.8%), primary schooling in 45 (25%), and finally completing graduate with 19 (10.5%). There was significant difference in knowledge between education level groups (p<0.0001). 35.6% of them didn't hear about Zika virus, while 30.6% hear about the virus in the previous few months and 26% knew about it in the last year. About 46 % don't know if there is a treatment of Zika virus infection while about 11 % they said yes there is a treatment. The majority of them 57 % don't take any measure to protect themselves from the virus, 39.4% who said no they don't know how to protect themselves. 44% don't know if there is a national or global organization to protect them or their family from the virus and 45.4 %they don't know while 10.6 % they said yes. When they asked how to protect themselves from mosquito's bite or decrease the mosquito's exposure 64.1% said all of above (keep the environment clean, clean the body and hands and sterilization of water, don't keep collect water) while 20.1% don't know the exact protection way. Conclusion: There is lack of public knowledge about Zika infection transmission, symptoms, treatment and prevention, thus needs more education by health facilities and social media.

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“…In one volunteer, a febrile illness of 4 days' duration developed 82 hours after subcutaneous inoculation of Zik a virus [12].…”

Section: Introductionmentioning

confidence: 99%

Zika Virus Infection.

Albeshry.¹,

Alastal.²,

Bahamdain.³

et al. 2017

IJAR

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“…R1118, R324 = WCCREC TMPPLSFRAKDGCW [1] W1118, W324 =WCCREC TMPPLSFWAKDGCW [2] Q1118, Q324 = WCCREC TMPPLSFQAKDGCW [3] The mutation site in polyprotein amino acid 1118 (numerically NS1 amino acid 324) is depicted in red. The data and analysis presented here support and expand the data and analysis presented by Freire et al [15] and therefore suggest that the observed Shannon entropy may be associated with immunological activity.…”

Section: Journal Of Medical Microbiology and Diagnosismentioning

confidence: 99%

“…Zika virus (ZIKV) is a single-stranded, positive sense RNA virus [1]. The Zika virus polyprotein consists of precursors of three structural proteins (capsid, precursor membrane (prM) and envelope (E) protein) and seven major nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) [2].…”

Section: Introductionmentioning

confidence: 99%

A Bioinformatic Glimpse of Human-Origin Zika Virus Polyprotein

Weltman¹

2017

J Med Microb Diagn

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An amino acid position with maximum Shannon information entropy and maximum cumulative mutual information is identified in Zika virus polyprotein. This amino acid position is used to sort the subset of Zika virus polyprotein mutations found exclusively in viruses isolated from human hosts but not from vector Aedes mosquitos. The identified mutational amino acid position is a component of a 20-mer peptide in the NS1 protein that has been reported with putative epitopic activity by Freire et al. It is suggested that the observed dual maxima bioinformatic parameters reported here for an exclusively human mutational site support the proposed function of that site in immunological activity.

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“…Complications of Zika virus infection include Guillain-Barré syndrome and microcephaly in the fetus of pregnant women infected in the first trimester. Treatment is again primarily supportive with preventive measures, such as insect repellant and protective clothing, paramount in anyone travelling to areas where they might be exposed to Zika virus [54].…”

Section: Zikamentioning

confidence: 99%

Got the Travel Bug? A Review of Common Infections, Infestations, Bites, and Stings Among Returning Travelers

2016

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The popularity of international travel continues to increase among Americans, even though they often experience subsequent illness on return from their journey. The pathogens responsible are not necessarily endemic to the destination itself but are often the result of poor sanitary conditions or activities engaged in while away. Skin disease ranks third among all medical concerns in returning travelers. This review addresses the pathogenesis, epidemiology, clinical presentation, and treatment of the most common skin diseases in returning travelers: insect bites and bedbugs, cutaneous larva migrans, scabies, tungiasis, myiasis, leishmaniasis, viral exanthems, and marine envenomation. Primary care physicians and dermatologists should be familiar with these illnesses and a general approach to their evaluation and management. Key PointsArthropod assault and infestation is a source of significant morbidity in returning travelers.Travelers should bring proper protective clothing and insect repellant when travelling to areas where biting insects are vectors of disease.Travelers should be acquainted with the hazards associated with local marine life if they plan on entering the water.

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Zika Virus: the Latest Newcomer

Cited by 171 publications

References 163 publications

Zika Virus Infection.

Zika Virus Infection.

A Bioinformatic Glimpse of Human-Origin Zika Virus Polyprotein

Got the Travel Bug? A Review of Common Infections, Infestations, Bites, and Stings Among Returning Travelers

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