Zinc-Amino Acid Complexes for Swine

Hill, David S.; Peo, E. R.; Lewis, A. J.; Crenshaw, J. D.

doi:10.2527/jas1986.631121x

Cited by 65 publications

(53 citation statements)

References 11 publications

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“…Similar results were previously reported by Hill et al [10]. In contrast, an improved growth rate of the piglets of similar live weight was observed by Adeola et al [1] by adding 100 mg·kg -1 of Zn in a corn-soybean meal diet containing 23 mg·kg -1 of Zn.…”

Section: Zn Balancesupporting

confidence: 90%

“…In pigs, similar observations are reported in the literature with diets containing Zn levels below the requirements [10,34,36] as well as with diets containing pharmacological Zn levels [9,31]. In chicks, inconsistent results were published.…”

Section: Bioavailability Of Zn Sourcessupporting

confidence: 63%

“…A zinc-methionine complex exhibited a higher bioavailability (206%) than ZnSO 4 in chicks fed corn-soybean meal diets [35]. In contrast, studies with pigs have failed to demonstrate differences in zinc bioavailability between organic and inorganic sources [7,10,34,36].…”

Section: Introductionmentioning

confidence: 99%

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Bioavailability of two sources of zinc in weanling pigs

Dourmad

Guinotte²,

Nys

2002

Anim. Res.

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-Thirty-two pigs, weaned at 28 days of age with an average body weight of 9 kg, were used in an experiment devoted to the assessment of the bioavailability of an organic Zn source (ZnOrg) compared to Zn sulfate. Pigs were fed a basal diet containing 28 mg·kg -1 of Zn supplemented with ZnSO 4 or ZnOrg to provide 0, 10, 20 and 30 mg·kg -1 of supplemental Zn. In order to reduce the amount and the variability of their Zn stores, pigs were fed the basal diet for a 7-day adjustment period preceding a 19-day experimental period. Growth performance and bone bending moment were not affected by the level nor the source of zinc. On the contrary, plasma zinc concentration and alkaline phosphatase activity (P < 0.001), bone zinc concentration (P < 0.001), liver and empty body zinc concentrations (P < 0.01) as well as the amount of Zn retained estimated both by the balance technique (BT) (P < 0.001) and by the comparative slaughter technique (CST) (P < 0.01) increased linearly in response to supplemental Zn. However, the two Zn sources exhibited a similar bioavailability. Twenty-seven percent of Zn intake was retained when measured by means of the balance technique, regardless of the dietary level or zinc source. Zn retention was 54% lower when measured by means of the CST as compared to the BT. (0)2 23 48 50 80; e-mail: jondreville@st-gilles.rennes.inra.fr de croissance et le moment de flexion de l'os n'ont été affectés ni par le niveau ni par la source de zinc supplémentaire. Au contraire, la teneur en zinc et l'activité de la phosphatase alcaline du plasma (P < 0,001), les teneurs en zinc osseuse (P < 0,001), hépatique et corporelle (P < 0,01) ainsi que la quantité de zinc retenu estimée par la technique du bilan (P < 0,001) et celle des abattages comparés (P < 0,01) augmentaient linéairement avec l'addition du zinc. Cependant, aucune différence entre les sources n'a été détectée. Le coefficient de rétention de zinc, estimé par la technique du bilan, était de 27 % en moyenne, indépendamment du niveau ou de la source de zinc supplémentaire. Estimée par la technique des abattages comparés, la rétention de Zn était de 54 % inférieure à la valeur obtenue selon la technique du bilan.porc / zinc / biodisponibilité / source / indicateur

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Section: Zn Balancesupporting

confidence: 90%

Section: Bioavailability Of Zn Sourcessupporting

confidence: 63%

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Bioavailability of two sources of zinc in weanling pigs

Dourmad

Guinotte²,

Nys

2002

Anim. Res.

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“…Bone Zn content is a reliable indicator for Zn bioavailability as it is highly correlated with dietary Zn content (Hill et al, 1986;Wedekind et al, 1994;Mohanna and Nys, 1998;Revy et al, 2003) and as it's maxima (plateau) is reached when dietary Zn content is higher than needed for other parameters. When dietary zinc content is increased, the approach of a physiological plateau for bone Zn, most probably explains the negative quadratic effect of supplemented Zn observed in broilers (ZN I 3 ZN I , P , 0.001 in Analysis II) and in piglets (ZN I 3 ZN I , P , 0.05 in Analysis II) and the negative interaction between supplemented Zn and supplemented phytases observed in broilers (ZN I 3 Phytase S , P , 0.05 in Analysis II).…”

Section: Description Of the Databasesmentioning

confidence: 99%

Bioavailability of zinc sources and their interaction with phytates in broilers and piglets

Schlegel

Sauvant

Jondreville

2013

Animal

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Zinc (Zn) is essential for swine and poultry and native Zn concentrations in feedstuffs are too low to meet their Zn requirement. Dietary Zn bioavailability is affected by phytate, phytase and Zn supplemented in organic form is considered as more bioavailable than inorganic sources. A meta-analysis using GLM procedures was processed using broiler and piglet databases to investigate, within the physiological response of Zn, (1) the bioavailability of inorganic and organic Zn sources (Analysis I); (2) the bioavailability of native and inorganic Zn dependent from dietary phytates, vegetal and supplemental phytase activity (Analysis II). Analysis I: the bioavailability of organic Zn relative to inorganic Zn sources ranged, depending on the variable, from 85 to 117 never different from 100 ( P . 0.05). The coefficients of determination of the regressions were 0.91 in broilers and above 0.89 in piglets. Analysis II: in broilers, bone Zn was explained by supplemental Zn (linear and quadratic, P , 0.001) and by supplemental phytase (linear, P , 0.001). In piglets, the interaction between dietary Zn and phytates/phytases was investigated by means of a new variable combining dietary phytic phosphorus (PP) and phytase activity. This new variable represents the remaining dietary PP after its hydrolysis in the digestive tract, mainly due to phytase and is called non-hydrolyzed phytic phosphorus (PP NH ). Bone Zn was increased with native Zn ( P , 0.001), but to a lower extent in high PP or low phytase diets (ZN N 3 PP NH , P , 0.001). In contrast, the increase in bone zinc in response to supplemental Zn ( P , 0.001) was not modulated by PP NH ( P . 0.05). The coefficients of determination of the regressions were 0.92 in broilers and above 0.92 in piglets. The results from the two meta-analyses suggest that (1) broilers and piglets use supplemented Zn, independent from Zn source; (2) broiler use native Zn and the use is slightly enhanced with supplemental phytase; (3) however, piglets are limited in the use of native Zn because of the antagonism of non-hydrolyzed dietary phytate. This explains the higher efficacy of phytase in improving Zn availability in this specie.

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“…On the other hand, Apgar et al (1994) did not verify any response of this combination in growth. Hill et al (1986) found higher feed intake with the use of zincmethionine, but feed conversion was not influenced when that chelate was combined with copper sulfate. Higher nominal zinc absorption was found by Hill et al (1987) for zinc-methionine as compared to zinc chloride, suggesting differences in transport rates between these two sources.…”

Section: Performance Of Poultry Fed Chelated Mineralsmentioning

confidence: 92%

Chelated minerals for poultry

Vieira

2008

Rev. Bras. Cienc. Avic.

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Organic minerals have been subject of an increasing number of investigations recently. These compounds can be considered the most significant event regarding commercial forms of minerals targeting animal supplementation in the last decades. Minerals, especially metals, are usually supplemented in poultry feeds using cheap saline sources and have never required a lot of attention in terms of quality. On the other hand, definitions of organic minerals are very broad and frequently lead to confusion when decision-making becomes necessary. Organic minerals include any mineral bound to organic compounds, regardless of the type of existing bond between mineral and organic molecules. Proteins and carbohydrates are the most frequent candidates in organic mineral combinations. Organic fraction size and bond type are not limitations in organic mineral definition; however, essential metals (Cu, Fe, Zn, and Mn) can form coordinated bonds, which are stable in intestinal lumen. Metals bound to organic ligands by coordinated bonds can dissociate within animal metabolism whereas real covalent bonds cannot. Chelated minerals are molecules that have a metal bound to an organic ligand through coordinated bonds; but many organic minerals are not chelates or are not even bound through coordinated bonds. Utilization of organic minerals is largely dependent on the ligand; therefore, amino acids and other small molecules with facilitated access to the enterocyte are supposed to be better utilized by animals. Organic minerals with ligands presenting long chains may require digestion prior to absorption. After absorption, organic minerals may present physiological effects, which improve specific metabolic responses, such as the immune response. Many studies have demonstrated the benefits of metal-amino acid chelates on animal metabolism, but the detection positive effects on live performance is less consistent.

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Zinc-Amino Acid Complexes for Swine

Cited by 65 publications

References 11 publications

Bioavailability of two sources of zinc in weanling pigs

Bioavailability of two sources of zinc in weanling pigs

Bioavailability of zinc sources and their interaction with phytates in broilers and piglets

Chelated minerals for poultry

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