Zinc Bromide

Organocatalytic Enantioselective Michael–Acetalization–Henry Reaction Cascade of 2-Hydroxynitrostyrene and 5-Oxohexanal for the Entry to the Hexahydro-6H-benzo[c]chromenones with Four Consecutive Stereogenic Centers and an Approach to Aflatoxin Analogues

“…During this process, in addition to the reduction of the acetal group on intermediate 3l , the ring opening and reduction of the cyclic tert -β-nitroalcohol group was observed in the NaBH 4 reduction reaction. , Zinc-catalyzed organic reactions have been applied in many organic syntheses . Among them, ZnBr 2 has been used for many synthetic transformations . Owing to its Lewis-acid property, we suspect that the Nef reaction of 9 could be achieved by the ZnBr 2 -mediated process, which will be a process with less basic or acidic reaction conditions than the traditional Nef process conditions, e.g., KOH, HCl, TiCl 4 , SnCl 4 , etc.…”

A Novel, Chemoselective and Efficient Microwave-Assisted Deprotection of Silyl Ethers with Selectfluor

“…Silyl esters and ethers are among the most frequently used protecting groups for acid and alcohol functionalities . A number of Lewis acids and other reagents have been reported to be effective in promoting cleavage of silyl-protected acids and alcohols and examples from the recent literature include the following: BF 3 , BCl 3 , sulfated SnO 2 , silica triflate, CuBr 2 , ZnBr 2 , NIS, TMSBr, and TMSCl . Many of these reagents provide the added advantage of promoting selective desilylation of bis-silyl ethers. , …”