Zinc(II) complexes of N(4)-monosubstituted thiosemicarbazones derived from pyridine-2-carbaldehyde: Structural and spectroscopic studies

Aminoguanidine-based bioactive proligand as AIEE probe for anticancer and anticovid studies

“…Additionally, the oxygen atom of the DMSO solvent engages in weaker intermolecular hydrogen bonding with C16-H16C/O3, mutually complementing and playing a crucial role in the crystal packing. 57 Moreover, phenylene rings of neighboring molecules participate in mutual p/p stacking interactions, with centroid-centroid distances measuring 3.5684(6) Å (Fig. S4 †).…”

“…Within the molecule, three conventional intramolecular hydrogen bonds occur between O1–H1A⋯N1, O2–H2⋯N4, and N2–H2A⋯O3, with respective hydrogen-acceptor distances of 1.88 Å, 1.89 Å, and 1.94 Å. Additionally, the oxygen atom of the DMSO solvent engages in weaker intermolecular hydrogen bonding with C16–H16C⋯O3, mutually complementing and playing a crucial role in the crystal packing. 57 Moreover, phenylene rings of neighboring molecules participate in mutual π⋯π stacking interactions, with centroid–centroid distances measuring 3.5684(6) Å (Fig. S4 † ).…”

Bis(thio)carbohydrazone Luminogens with AIEE and ACQ Features and Their In Silico Investigations with SARS‐CoV‐2

“…The phenylene rings of adjacent molecules form mutual π π stacking interactions with a centroid‐centroid distances of 3.613 Å. The oxygen atoms of the two DMSO, of which one solvent is found disordered, are engaged in strong O H−N hydrogen bonding, while the weaker intermolecular hydrogen bonding between C16‐H16B O2 and C17‐H17C O3 are mutually complementing and plays an important role in the crystal structure packing [54] . Interestingly, a halogen bond interaction is found between I4 O4 at a distance of 3.435(5) Å, which plays a key role in the 1D supramolecular network formation interconnected through the hydrogen bonding involving N2‐H2 O4 (Figure 2).…”

“…ChemistrySelect hydrogen bonding, while the weaker intermolecular hydrogen bonding between C16-H16B� � �O2 and C17-H17C� � �O3 are mutually complementing and plays an important role in the crystal structure packing. [54] Interestingly, a halogen bond interaction is found between I4� � �O4 at a distance of 3.435(5) Å, which plays a key role in the 1D supramolecular network formation interconnected through the hydrogen bonding involving N2-H2� � �O4 (Figure 2).…”

Bis{N′-[3-(4-nitrophenyl)-1-phenylprop-2-en-1-ylidene]-N-phenylcarbamimidothioato}zinc(II): crystal structure, Hirshfeld surface analysis and computational study

“…The pharmacological activities of metal complexes are usually enhanced compared to their parent free thiosemicarbazone ligands (Mathews & Kurup, 2021). The enhanced activities may be attributed to the redox potential and increased lipophilicity of the metal complexes (Rapheal et al, 2021). Transition-metal complexes derived from thiosemicarbazones exhibit widespread pharmacological activities inclusive of anti-tubercular (Khan et al, 2020), antimicrobial (Nibila et al, 2021), anti-bacterial (Prajapati & Patel, 2019), anti-malarial (Savir et al, 2020), anti-diabetic (Kumar et al, 2020), anti-viral (Rogolino et al, 2015) and anti- ISSN 2056-9890 cancer (Anjum et al, 2019;Balakrishnan et al, 2019).…”