Zinc intakes and plasma concentrations in men with osteoporosis: the Rancho Bernardo Study

Hyun, Taisun; Barrett‐Connor, Elizabeth; Milne, David B.

doi:10.1093/ajcn/80.3.715

Cited by 119 publications

(73 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the older group, serum Zn concentration was not different (13.1073.11 mmol/l for women and 13.1072.97 mmol/l for men) and in agreement with Ravaglia et al (2000) who reported 13.7871.67 mmol/l for a population aged 65-89 y old. Finally, our data confirm the Rancho Bernardo study (Hyun et al, 2004) in which, for a mean dietary intake of 11.274.3 mg (in 396 men-aged 45-92 y), the mean serum Zn concentration was 12.770.1 mmol/l.…”

Section: Discussionsupporting

confidence: 89%

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

et al. 2005

View full text Add to dashboard Cite

Objective: Inadequate intakes of micronutrients in elderly negatively affect the nutritional status. Zinc is an essential micronutrient in the elderly, especially in relation to its impact on immune function, bone mass, cognitive function and oxidative stress. However, data are lacking on zinc intake and status during normal ageing. In this study, we evaluate the intake and status of zinc in late middle-aged and older free-living subjects. Design: Dietary zinc intake and zinc status in 188 middle-aged subjects from Clermont-Ferrand (Fr) and Coleraine (UK), and in 199 older subjects from Grenoble (Fr) and Roma (It) were assessed at the entry in the ZENITH study. Results: In relation to the zinc RDA for people older than 55 y, zinc intakes in most of the middle-aged and older subjects (more than 96%) in the present study were adequate. Older people had significantly lower (Po0.01) energy intakes as compared to middle-aged. Zinc intake expressed per MJ was also significantly (Po0.01) higher in older people compared to middle-aged. Erythrocyte and urinary zinc concentrations were significantly (Po0.001) higher in middle-aged subjects compared to older ones. The prevalence of biological Zn deficiency in free-living ageing European people was low (o5%). Conclusion:The results of the present study showed a relatively low prevalence of zinc deficiencies in healthy free-living late middle-age and older subjects. These results should be useful for health professionals to have reference data on zinc intake and status for a healthy ageing.

show abstract

Section: Discussionsupporting

confidence: 89%

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Although there are few reports (Hyun et al, 2004) on the effect of zinc intake in elderly people, our results suggest that the supply of zinc through meals in elderly people has a beneficial effect. In order to contribute towards a healthy life, it is important to assay serum zinc levels for early screening and to improve zinc nutritional status by diet or temporary supplementation in elderly people (Takeda et al, 2004;Andriollo-Sanchez et al, 2005;Kurasawa and Kubori, 2006).…”

Section: Discussioncontrasting

confidence: 49%

Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan

et al. 2006

View full text Add to dashboard Cite

Objective: Elderly patients often have impaired taste, nausea, anorexia and delayed healing of decubitus. In many of these patients, serum zinc levels are low and they respond to zinc supplementation. To date, no epidemics of zinc deficiency have been reported in Japan. We studied the prevalence of zinc deficiency and its causative factors in a typical local town in Japan. Design: Cross-sectional study. Setting: Nagano Prefecture (central Japan). Subjects and methods: Serum zinc levels were measured in 1009 habitants (18-96 years old) who participated in an annual mass health examination program of the City in 2003. Of all subjects, 86 with low serum zinc (o65 mg/dl) or high zinc (X90 mg/ dl) levels were randomly selected, and a dietary survey using 24-h recalling methods for 2 consecutive days was performed in 2004. Among them, blood was collected in the morning from 50 subjects (26-94 years old). Results: The percentage of those with low serum zinc levels (2.5th percentile of Americans) was 37.9% in the elderly (X60 years old). The age-adjusted prevalence of low serum zinc was 21.1% in the aged population. A positive correlation was detected between zinc intake and serum zinc levels in elderly subjects (X60 years old). Conclusions: The possibility of zinc deficiency in adult inhabitants in central Japan rises with age. The deficiency correlates with dietary zinc intake. Sponsorship: This research was supported by a grant from local government officials in Tomi City (2004) and the funding of Fancl Corporation.

show abstract

“…The association between dietary zinc intake and serum zinc in this study is concordant with the results of Taisun et al [23] and Neggers et al [24]. In addition, Taisun et al demonstrated that plasma zinc was correlated with total zinc intake, including supplementary intake together with dietary zinc intake [23].…”

Section: Discussionsupporting

confidence: 92%

“…The results of this study demonstrated that serum zinc concentration in these osteoporotic women was significantly lower than the normal range (100-140 µg/dL), which is similar to the results obtained from the second National Health and Nutrition Interview Survey in 1976-80 [16], and an epidemiological survey conducted in Rome [17]. Although the results obtained suggested that low serum zinc concentrations may have been a result of low zinc dietary intake, Relea et al [18] and Herzberg et al [19] reported that urinary zinc excretion was higher in osteoporotic women.…”

Section: Discussionsupporting

confidence: 86%

Effect of zinc supplementation on serum zinc and calcium levels in postmenopausal osteoporotic women in Tabriz, Islamic Republic of Iran

Mahdavi-Roshan

Golzarand²,

Taramsari³

2013

East Mediterr Health J

View full text Add to dashboard Cite

Research on the zinc status of osteoporotic women is scarce. This randomized, double-blind, placebocontrolled clinical trial assessed the effect of zinc supplementation on serum zinc and calcium levels in postmenopausal osteoporotic women. A sample of 60 women referred to a rheumatology clinic in Tabriz were randomly divided into intervention (220 mg zinc sulfate daily) and placebo groups. Anthropometric indices, dietary intake of zinc and calcium and serum zinc and calcium were assessed at baseline and after 60 days. Mean serum zinc concentrations were markedly lower than the normal range at baseline, but mean serum calcium levels were normal. In the intervention group serum zinc levels were significantly higher after 60 days [120.5 (SD 7.5) versus 70.5 (SD 4.6) µg/dL] while serum calcium levels were unchanged [8.6 (SD 0.1) versus 9.1 (SD 0.3) mg/dL]. The placebo group showed no significant changes in zinc or calcium levels. Postmenopausal osteoporotic women may benefit from zinc supplementation.

show abstract

Zinc intakes and plasma concentrations in men with osteoporosis: the Rancho Bernardo Study

Abstract: Dietary zinc intake and plasma zinc each have a positive association with BMD in men.

Cited by 119 publications

References 37 publications

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan

Effect of zinc supplementation on serum zinc and calcium levels in postmenopausal osteoporotic women in Tabriz, Islamic Republic of Iran

Contact Info

Product

Resources

About