Low-dimensional black phosphorus (LDBP) materials have emerged, with considerable application potential in sensing due to their unique folded structures and remarkable physicochemical properties. These include anisotropies, layer-dependent and tunable band gaps, high carrier mobilities, high current switching ratios, and excellent electron donor capacities. As a type of supporting material that is favorable to signal transmission or reception, LDBP is widely researched in piezoelectric, flexible, chemical, and biomolecular sensors. This review summarizes the synthetic methods, properties, and modification strategies of LDBP, and then mainly focuses on the research progress in LDBP-based sensor applications, including physical and chemical sensors and biosensors. The major issues in LDBP-based sensor applications are also discussed. Finally, the prospects and challenges in the field of LDBPbased sensors are analyzed.