Zinc oxide nano-rods based glucose biosensor devices fabrication

Wahab, H. A.; Salama, Ahmed; Saeid, Aziza A. El; Willander, Magnus; Nur, Omer; Battisha, I. K.

doi:10.1016/j.rinp.2018.02.077

Cited by 47 publications

(25 citation statements)

References 13 publications

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“…12 In recent research advancements, ZnO has received considerable attention for solar cells, 12 lasers, 13 spintronics, 14 transparent conductive oxide, 12 catalysis, 15 bioimaging, 16 and biosensors. 17 Among dimensional ZnO nanomaterials, one-dimensional (1D) ZnO nanostructures with defect free high crystallinity are a particular interest due to their unique and inherent intrinsic chemical, electrical, physical, and mechanical properties compared to that of bulk and thin lm counterpart. 10 However, synthesis of defect free 1D ZnO nanostructures, with desired morphology and composition, has been challenging as most growth techniques involve either high-cost fabrication processes or high temperature wet-chemical syntheses performed in highly toxic solvents.…”

Section: Introductionmentioning

confidence: 99%

Band gap engineered zinc oxide nanostructures via a sol–gel synthesis of solvent driven shape-controlled crystal growth

et al. 2019

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Section: Introductionmentioning

confidence: 99%

Band gap engineered zinc oxide nanostructures via a sol–gel synthesis of solvent driven shape-controlled crystal growth

et al. 2019

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“…The chemical properties and organization of ZnO NRs can be modulated by the synthesis procedure, influencing their ability to adsorb biomolecules. When aiming for biosensor applications, ZnO NRs are typically prepared by a hydrothermal procedure 7 , 9 , 10 ; however, this method requires the use of high temperature and pressure, limiting its use on flexible polymeric materials. Electrodeposition is an alternative and affordable method that can also deliver high-quality ZnO NRs 11 .…”

Section: Introductionmentioning

confidence: 99%

Flexible ZnO-mAb nanoplatforms for selective peripheral blood mononuclear cell immobilization

Babu

Pinheiro

Marques

et al. 2020

Sci Rep

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Cancer is the second cause of death worldwide. This devastating disease requires specific, fast, and affordable solutions to mitigate and reverse this trend. A step towards cancer-fighting lies in the isolation of natural killer (NK) cells, a set of innate immune cells, that can either be used as biomarkers of tumorigenesis or, after autologous transplantation, to fight aggressive metastatic cells. In order to specifically isolate NK cells (which express the surface NKp30 receptor) from peripheral blood mononuclear cells, a ZnO immunoaffinity-based platform was developed by electrodeposition of the metal oxide on a flexible indium tin oxide (ITO)-coated polyethylene terephthalate (PET) substrate. The resulting crystalline and well-aligned ZnO nanorods (NRs) proved their efficiency in immobilizing monoclonal anti-human NKp30 antibodies (mAb), obviating the need for additional procedures for mAb immobilization. The presence of NK cells on the peripheral blood mononuclear cell (PBMCs) fraction was evaluated by the response to their natural ligand (B7-H6) using an acridine orange (AO)-based assay. The successful selection of NK cells from PBMCs by our nanoplatform was assessed by the photoluminescent properties of AO. This easy and straightforward ZnO-mAb nanoplatform paves the way for the design of biosensors for clinic diagnosis, and, due to its inherent biocompatibility, for the initial selection of NK cells for autotransplantation immunotherapies.

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“…Several reports have demonstrated the application of ZnO as biosensors, i.e. in DNA immobilization [180], in glucose level detection [176,177,181], for cardiac biomarker detection [179,182,183] and also for cancer diagnostic [178,184,185].…”

Section: Zinc Oxidementioning

confidence: 99%

“…Gallay et al [176] was able to produce a ZnO nanowire-based glucose sensor capable of detecting very low glucose concentrations of about 9 M. Wahab et al [181] used ZnO nanorods for the detection of glucose with concentration ranging from 1 M to 10 mM. Wang et al [177] synthesized ZnO nanocombs, forming a highly porous structure, that were then immobilized with glucose oxidase, showing a detection limit of 0.02 mM.…”

Section: Zinc Oxidementioning

confidence: 99%

Metal oxide nanostructures for sensor applications

Nunes

Pimentel

Gonçalves

et al. 2019

Semicond. Sci. Technol.

260

119

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Human health, environmental protection and safety are just a few examples of current humankind main concerns, that drive the scientific community to develop sensors able to precisely monitor and alert to possible harms in real time. Over the years, semiconductor metal oxide-based materials have been largely employed as sensors dedicated to several applications, being particularly interesting at the nanometer scale, since it is largely known that smaller crystallite size enhances sensor's performance. Moreover, these materials are highly appealing as they can be produced by low-cost wet-chemical synthesis routes and are in general nontoxic, earth abundant and low-cost. This manuscript extensively reviews the recent developments of nanostructured semiconductor metal oxide sensors ranging from gas to humidity sensors, including ultraviolet (UV) sensors and biosensors. Zinc oxide (ZnO), titanium dioxide (TiO2), tungsten trioxide (WO3), copper oxide (CuO and Cu2O), tin oxide (SnO and SnO2), and vanadium oxide (VO2, V2O5)-based sensors either as nanoparticles or as continuous films/layers are described. Their sensing properties are correlated to size, shape, presence of defects, doping elements, amongst other relevant parameters. Different techniques and methods of fabricating these materials are addressed. The review is concluded with novel approaches for functionalization and future perspectives for sensor developments.

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Zinc oxide nano-rods based glucose biosensor devices fabrication

Cited by 47 publications

References 13 publications

Band gap engineered zinc oxide nanostructures via a sol–gel synthesis of solvent driven shape-controlled crystal growth

Band gap engineered zinc oxide nanostructures via a sol–gel synthesis of solvent driven shape-controlled crystal growth

Flexible ZnO-mAb nanoplatforms for selective peripheral blood mononuclear cell immobilization

Metal oxide nanostructures for sensor applications

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