Zinc Transporters in the Endocrine Pancreas

Bosco, Mariea Dencey; Drogemuller, Chris; Zalewski, Peter D.; Coates, P. Toby

doi:10.1007/978-94-007-6884-0_42-2

Cited by 2 publications

(1 citation statement)

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“…It has been found that 70-80% of the ingested Zn is excreted in saliva, sweat and urine. It has been shown that the pancreas cells have a high level of Zn, but the quantities secreted by the pancreas are unknown (Bosco et al, 2015). Zinc deficiency and malabsorption have been described previously in patients with alcoholic pancreatitis and chronic pancreatitis (Girish et al, 2009;Vujasinovic et al, 2019).…”

Section: Resultsmentioning

confidence: 98%

Estimation of some vital trace elements in patients with acute pancreatitis: A case-control study

Al-Fartusie

Farhan

Al-Bairmani

et al. 2022

Braz. J. Pharm. Sci.

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Trace elements have an important influence on the living system and play a major role in a variety of processes necessary for life. This case study was conducted as an attempt to expand our knowledge of the relationship between trace elements and their effect on acute pancreatitis. Sixty-five patients diagnosed with acute pancreatitis with mean age 43.6 years, along with sixtyfive healthy volunteers with a mean age 45.7 years, were included in this study. The obtained results indicated a significant increase in the Cu, Ni and Cr levels, and a significant decrease in the Zn, Mg and Fe levels for acute pancreatitis patients compared with the control group (p <0.001). In addition, a remarkable increase in the Cu/Zn ratio was observed in patients. The current work provides important evidence of correlation between changes in copper and zinc levels and the risk of acute pancreatitis. Also, an increased Cu/Zn ratio may be a useful indication for the diagnosis and monitoring of acute pancreatitis. Moreover, the current study concluded that there is a possible relationship of Mg, Fe, Ni and Cr with acute pancreatitis. Thus, it can be suggested that these elements are reliable to provide indications for warning of the risk of acute pancreatitis.

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Section: Resultsmentioning

confidence: 98%