Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies

Gumbarewicz, Ewelina; Jarząb, Agata; Stepulak, Andrzej; Kukuła-Koch, Wirginia

doi:10.3390/ijms232415545

Cited by 6 publications

(2 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mahluji et al (2013) demonstrated in their study that Z. officinale can reduce insulin levels in patients with type 2 diabetes. Additionally, Z. officinale supplementation shows supportive effects in the treatment of inflammatory disorders and metabolic syndrome (Gumbarewicz et al 2022).…”

Section: Fidelity Level (Fl) Of Medicinal Plantsmentioning

confidence: 99%

Ethnobotanical study of medicinal plants by indigenous community of Aek Guo Village, Mandailing Natal District, Indonesia

RAMBEY,

NELASUFA,

ATHORIEZ

et al. 2024

Biodiversitas

View full text Add to dashboard Cite

Abstract. Rambey R, Nelasufa F, Athoriez APM, Solihin, Rahmawaty, Susilowati A, Afifuddin Y. 2024. Ethnobotanical study of medicinal plants by indigenous community of Aek Guo Village, Mandailing Natal District, Indonesia. Biodiversitas 25: 1046-1056. Aek Guo Village, Mandailing Natal District, Indonesia, falling under the jurisdiction of Forest Management Unit or Kesatuan Pengelolaan Hutan (KPH) IX Panyabungan, serves as a home for the Mandailing indigenous tribe, primarily engaged in agriculture with a significant dependence on the forest for sustenance. Within the cultural fabric of the Aek Guo community, there exists a profound tradition of employing medicinal plants as an alternative form of treatment, a practice deeply rooted in ethnobotanical knowledge passed down through generations. The study aimed to identify the diverse array of medicinal plants, their utilization practices, and key parameters such as Use Value (UV), Family Use Value (FUV), Plant Part Value (PPV), and Fidelity Level (FL) associated with their applications. A comprehensive approach that integrates qualitative and quantitative methods, the study involves semi-structured interviews and meticulous documentation. The findings reveal a rich repertoire of 66 plant species distributed across 36 families, constituting a vital component of the Aek Guo community. Noteworthy is the pre-eminence of ginger (Zingiber officinale) with the highest UV value (0.68), while paku gajah (Angiopteris evecta) being the lowest (0.01). Family Use Value (FUV) demonstrated variations, with Fabaceae leading the chart (0.39), and Simaroubaceae recording the lowest value (0.01). A closer examination of Plant Part Value (PPV) indicated a preference for leaves, comprising 56.06% of the utilized plant parts, while flowers contribute minimally at 1.51%. Fidelity Level (FL) values, crucial for assessing the significance of particular plants within the community, peak for kumis kucing (Orthosiphon aristatus) and ginger (Z. officinale) at 22.54%. In contrast, jerangau (Acorus calamus), pasak bumi (Eurycoma longifolia), salam (Syzygium polyanthum), and paku gajah (A. evecta) exhibit the lowest FL values at 1.41%. These findings contribute significantly to the broader understanding of ethnobotanical practices across different Mandailing communities, with potential implications for conservation, healthcare, and sustainable resource management.

show abstract

Section: Fidelity Level (Fl) Of Medicinal Plantsmentioning

confidence: 99%

Ethnobotanical study of medicinal plants by indigenous community of Aek Guo Village, Mandailing Natal District, Indonesia

RAMBEY,

NELASUFA,

ATHORIEZ

et al. 2024

Biodiversitas

View full text Add to dashboard Cite

show abstract

“…Numerous researchers studied the effects of different natural extracts ( Aloe vera , Zingiber officinale , Tabernaemontana divaricata , etc.) on the pathophysiological mechanisms of DM, showing beneficial effects on hyperglycemia [ 3 , 4 , 5 ] and on diabetes-related cardiovascular impairments [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Gold Nanoparticles Functionalized with Cornus mas L. Fruit Extract on the Aorta Wall in Rats with a High-Fat Diet and Experimental-Induced Diabetes Mellitus—An Imaging Study

et al. 2023

View full text Add to dashboard Cite

Diabetes mellitus and high-fat diets trigger the mechanisms that alter the walls of blood vessels. Gold nanoparticles, as new pharmaceutical drug delivery systems, may be used in the treatment of different diseases. In our study, the aorta was investigated via imaging after the oral administration of gold nanoparticles functionalized with bioactive compounds derived from Cornus mas fruit extract (AuNPsCM) in rats with a high-fat diet and diabetes mellitus. Sprague Dawley female rats that received a high-fat diet (HFD) for 8 months were injected with streptozotocin to develop diabetes mellitus (DM). The rats were randomly allocated into five groups and were treated, for one additional month with HFD, with carboxymethylcellulose (CMC), insulin, pioglitazone, AuNPsCM solution or with Cornus mas L. extract solution. The aorta imaging investigation consisted of echography, magnetic resonance imaging and transmission electron microscopy (TEM). Compared to the rats that received only CMC, the oral administration of AuNPsCM produced significant increases in aorta volume and significant decreases in blood flow velocity, with ultrastructural disorganization of the aorta wall. The oral administration of AuNPsCM altered the aorta wall with effects on the blood flow.

show abstract

Gingerol: extraction methods, health implications, bioavailability and signaling pathways

Samota,

Rawat,

Kaur

et al. 2024

Sustainable Food Technol.

View full text Add to dashboard Cite

show abstract

Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies

Cited by 6 publications

References 61 publications

Ethnobotanical study of medicinal plants by indigenous community of Aek Guo Village, Mandailing Natal District, Indonesia

Ethnobotanical study of medicinal plants by indigenous community of Aek Guo Village, Mandailing Natal District, Indonesia

Effects of Gold Nanoparticles Functionalized with Cornus mas L. Fruit Extract on the Aorta Wall in Rats with a High-Fat Diet and Experimental-Induced Diabetes Mellitus—An Imaging Study

Gingerol: extraction methods, health implications, bioavailability and signaling pathways

Contact Info

Product

Resources

About