Zink und seine anorganischen Verbindungen [MAK Value Documentation in German language, 2010]

doi:10.1002/3527600418.mb744066d0049

The MAK‐Collection for Occupational Health and Safety 2012

DOI: 10.1002/3527600418.mb744066d0049

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Zink und seine anorganischen Verbindungen [MAK Value Documentation in German language, 2010]

Abstract: Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 49. Lieferung, Ausgabe 2010 Der Artikel enthält folgende Kapitel: Allgemeiner Wirkungscharakter Wirkungsmechanismus Toxikokinetik und Metabolismus Aufnahme, Verteilung, Ausscheidung Metabolismus Erfa… Show more

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Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?

et al. 2023

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Exposure to airborne substances such as gases, vapours, and particles remains a relevant health risk in many workplaces. A current topic and cause for discussion is the investigation of the health effects of particles containing zinc oxide (ZnO). Among other data, those collected from our study on human exposure data of ZnO in 2018 prompted the National Research Centre for the Working Environment 2021 to formulate a new, sharply lowered proposed occupational exposure limit (OEL) for zinc in workplaces. Since the publication of the Danish report, further studies have been conducted with ZnO. In the following text, all arguments for deriving this new limit value for zinc from the report are discussed, extended with the more recent data since 2018. It should be noted that especially the application of time extrapolation factors needs further discussion and harmonization between regulatory authorities. From our point of view, the data situation can justify a higher OEL for zinc than that proposed by the Danish National Research Centre for the Working Environment.

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Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?

et al. 2023

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Zinc fever in a painter and varnisher: a case report

Belting,

Eisenhawer,

Merget

et al. 2024

J Med Case Reports

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Background Zinc fever is well described in medical literature, particularly in workers after handling zinc-containing materials at high temperatures e.g., in the welding of hot-dip galvanized steel sheets. It is not known whether zinc fever also occurs at low temperatures. Case presentation We present the case of a 33-year-old Caucasian atopic painter and varnisher with work-related dyspnea, sweating, as well as multiple occurrences of fever. He was sent to Institute for Prevention and Occupational medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA) for the evaluation of isocyanate asthma, but an inhalative challenge with hexamethylene diisocyanate was negative. Since symptoms were closely related to the use of zinc coatings at room temperature without adequate protective measures, the diagnosis of zinc fever was made. After exposure cessation the worker immediately became symptom-free. The work as painter and varnisher may be associated with various exposures to hazardous substances. Besides solvents, epoxy compounds and isocyanates, which can cause obstructive respiratory diseases; additionally, zinc-containing agents should be considered as health hazards. Conclusions This case demonstrates that zinc fever may occur also after application of zinc coatings by spray painting at low temperatures.

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Zink und seine anorganischen Verbindungen [MAK Value Documentation in German language, 2010]

Abstract: Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 49. Lieferung, Ausgabe 2010 Der Artikel enthält folgende Kapitel: Allgemeiner Wirkungscharakter Wirkungsmechanismus Toxikokinetik und Metabolismus Aufnahme, Verteilung, Ausscheidung Metabolismus Erfa… Show more

Cited by 2 publications

References 77 publications

Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?

Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?

Zinc fever in a painter and varnisher: a case report

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