Clastic sediment composition constitutes a key archive of Earth history, controlled by allogenic and autogenic processes that impact weathering, erosion, sediment transfer, and deposition. Deciphering those processes can provide valuable insights into ancient and modern tectonic, geomorphic, climatic, and anthropogenic controls that shape sediment routing systems over a wide range of temporal and spatial scales. However, in order to clearly identify the controls on sediment composition, it is necessary to exclude sources of bias that may mask or diminish the original provenance signal. Such biases may be natural, including mineral fertility, sediment recycling, and grain size, or analytical. This special collection arises from the fifth meeting of the working group on sediment generation held at the University Milano‐Bicocca in Milan, Italy, from 28 to 30 June 2022. The collation includes studies that investigate biasing factors affecting all steps of the sediment cascade and all stages of sample collection, preparation, and analysis, as well as case studies that aim to disentangle original provenance signals from geological, environmental, or analytical noise.